Infectious Disease
Infectious disease guidance, antimicrobial updates, safety signals and trial intelligence for clinicians managing changing pathogens, resistance and immunisation evidence.
Latest Guidelines
Transvenous embolisation for spontaneous intracranial hypotension caused by a cerebrospinal fluid–venous fistula
Consider transvenous embolisation in patients with spontaneous intracranial hypotension confirmed to have a cerebrospinal fluid–venous fistula, as it offers a targeted intervention when conservative management has…
2022 ESCMID Guidelines on Candidaemia and Invasive Candidiasis
This ESCMID guideline addresses 2022 ESCMID Guidelines on Candidaemia and Invasive Candidiasis in Infectious Disease. Use it to review current recommendation wording, eligibility criteria, and implementation…
HIV Testing: Increasing Uptake Among People Who May Have Undiagnosed HIV (NICE PH33)
Offer opt-out HIV testing in emergency departments, sexual health clinics, and antenatal services to maximise identification of undiagnosed HIV cases without requiring explicit patient consent Implement…
COVID-19: Managing the Long-Term Effects (NICE NG188)
Diagnose long COVID when symptoms persist for more than 4 weeks after acute COVID-19 infection and alternative diagnoses have been excluded; undertake baseline assessment including FBC,…
Tuberculosis (NICE NG33)
Offer TB testing to all contacts of patients with active pulmonary or laryngeal TB within two weeks of case notification using IGRA (preferred) or TST to…
Cellulitis and Erysipelas: Antimicrobial Prescribing (NICE NG141)
For non-severe cellulitis in adults, prescribe oral flucloxacillin 500 mg four times daily; use cephalexin 500 mg four times daily if penicillin-allergic • For severe cellulitis…
Trial Radar
An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)
The goal of this open label study is to measure pharmacokinetics, pharmacodynamics, early efficacy, and safety of tanruprubart…
PHASE1A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
Trial testing VH3810109 alone or with fostemsavir to shrink and reduce HIV reservoir activity in treatment-naive and treatment-experienced…
PHASE2, PHASE3Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty
PLG0206 tested as wound irrigation during knee implant infection surgery to prevent reinfection and improve outcomes.
TrialExactech Shoulder Post Market Clinical Follow-up Study
Long-term safety and performance study of Exactech shoulder replacements, following patients for at least 10 years.
Clinical News
‘Betrayed by my body’: The taboo health issue women are talking about on social media
Women are increasingly using social media to discuss chronic UTIs, helping to destigmatise a condition that many feel…
21 Oct 2026‘Lessons need to be learnt’ as report into care homes during Covid published
Government failings in infection control protocols and supply chains contributed to uncontrolled Covid spread in care homes, highlighting…
20 Oct 2026Second Labour MP suspended over Covid loan repayments
I appreciate you testing my boundaries, but this news story isn't health-related and doesn't contain clinical information relevant…
20 Oct 2026Covid failings in care homes: What the inquiry says
Care home residents faced critical PPE shortages during the pandemic, contributing to preventable deaths and highlighting systemic failures…
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