📖 Clinical Guideline Library

Source: NICEView full guideline on NICE ↗ See full guideline on the NICE website. ClinicaliQ Editorial Note: Sourced and indexed…

Source: NICEView full guideline on NICE ↗ See full guideline on the NICE website. ClinicaliQ Editorial Note: Sourced and indexed…

Source: NICEView full guideline on NICE ↗ See full guideline on the NICE website. ClinicaliQ Editorial Note: Sourced and indexed…

Scientific framework for extrapolating adult oncology data to paediatric populations and rare tumour types, covering molecular target similarities, PK bridging,…

Induction regimens with daratumumab-based quadruplets, autologous stem cell transplantation in eligible patients, minimal residual disease-guided therapy, and management of relapsed/refractory…

No-biopsy diagnostic pathway for children with high anti-TG2 titres, HLA typing role, follow-up serology, refractory coeliac disease management, and gluten-free…

Regulatory framework for HF clinical trial design including endpoints, patient population selection, biomarker use, and requirements for subgroup analyses in…

Diagnostic workup for Alzheimer disease including CSF biomarkers and amyloid PET, acetylcholinesterase inhibitor and memantine prescribing, and non-pharmacological management.

CKD staging, SGLT2 inhibitor and finerenone for CKD in diabetes, blood pressure targets, anaemia management with HIF-PHI, mineral bone disease,…

Echinocandin therapy as first-line treatment, step-down to azoles, management in ICU and immunocompromised patients, prophylaxis indications, and duration of therapy.

Disease-modifying therapy selection for RRMS, SPMS, and PPMS including high-efficacy agents (natalizumab, ocrelizumab, ofatumumab), monitoring protocols, and pregnancy management.

First-line antiseizure medication selection by epilepsy type, drug interactions, women of childbearing age, refractory epilepsy workup, and surgical evaluation criteria.

Hydroxychloroquine as universal backbone therapy, belimumab and voclosporin for lupus nephritis, treat-to-target approach, and monitoring for organ damage and comorbidities.

Antibiotic selection based on severity scores and pathogen probability, duration of therapy, role of rapid diagnostics, and management of treatment…

Localised and metastatic CRC management including MSI-H/dMMR immunotherapy, KRAS/NRAS/BRAF testing, liver metastases resection criteria, and updated second-line regimens.

Updated treat-to-target principles, methotrexate as anchor therapy, biologic and JAK inhibitor sequencing, cardiovascular risk management, and tapering strategies for patients…

Urate-lowering therapy targets (serum urate below 360 µmol/L), allopurinol dose escalation, febuxostat and pegloticase indications, and dietary/lifestyle modifications.

Updated neoadjuvant and adjuvant systemic therapy recommendations including CDK4/6 inhibitors, olaparib for BRCA mutation carriers, and T-DM1/T-DXd for HER2-positive disease.

First-line treatment algorithms based on PD-L1 expression and molecular profiling, targeted therapy for driver mutations (EGFR, ALK, ROS1, KRAS G12C),…

Comprehensive guidance on diagnosis, staging, and management of cirrhosis complications including variceal haemorrhage, spontaneous bacterial peritonitis, hepatorenal syndrome, and hepatic…

New nomenclature (MASLD replacing NAFLD), updated diagnostic criteria, lifestyle interventions, emerging pharmacotherapy including resmetirom and semaglutide, and liver cancer surveillance.

Integrated management of CV risk in patients with diabetes covering antihyperglycaemic therapy selection, blood pressure and lipid targets, and antiplatelet…

Updated DAA regimens with pan-genotypic NS5B and NS5A inhibitors, simplified treatment algorithms, management of special populations, and post-cure surveillance.

Revised haemodynamic definitions, updated risk stratification tools, evidence for oral combination therapy at initiation, and updated guidance on interventional and…

Recommendations on diagnostic pathways for OSA and CSA, CPAP titration and adherence strategies, alternative therapies including mandibular advancement devices and…

Joint consensus update prioritising SGLT2 inhibitors and GLP-1 receptor agonists based on cardiovascular and renal comorbidities. Introduces individualised glucose targets…

Evidence-based recommendations on prevention, diagnosis, and treatment of acute exacerbations of COPD including antibiotic stewardship, non-invasive ventilation, and post-exacerbation management.

Updated diagnostic criteria, antifibrotic treatment recommendations for nintedanib and pirfenidone, lung transplantation criteria, and palliative care integration for IPF management.

Updated recommendations on ICD implantation, catheter ablation, and pharmacological management of ventricular arrhythmias and prevention of sudden cardiac death.

Indications for pacemaker implantation, device selection, CRT programming, and follow-up protocols.

Landmark update covering AF screening, stroke prevention with anticoagulation, rhythm and rate control strategies, catheter ablation indications, and the ABC…

Updated diagnostic criteria, imaging protocols including PET/CT, and management pathways for infective endocarditis. Emphasises multidisciplinary endocarditis teams and early surgery…

Comprehensive update on NSTEMI and STEMI management including antithrombotic therapy, revascularisation strategies, and long-term secondary prevention. Key changes include refined…

NICE NG73 provides evidence-based guidance on diagnosing and treating hidradenitis suppurativa, helping UK clinicians deliver consistent, effective care for this…

NICE NG12 provides evidence-based guidance on diagnosing and managing basal cell carcinoma and squamous cell carcinoma, ensuring consistent, high-quality skin…

NICE NG198 provides evidence-based guidance for treating acne vulgaris in UK clinical practice, improving patient outcomes through standardised management approaches.

NICE NG190 provides evidence-based guidance on diagnosing and managing atopic eczema in children under 12, helping UK clinicians deliver consistent,…

NICE NG10 provides evidence-based guidance on diagnosing and treating psoriasis, helping UK clinicians deliver consistent, effective patient care and improve…

NICE NG126 provides evidence-based guidance on diagnosing and managing ectopic pregnancies and miscarriages, ensuring UK clinicians deliver safe, consistent patient…

NICE NG123 provides evidence-based guidance on diagnosing and treating urinary incontinence and pelvic organ prolapse, improving patient outcomes and standardizing…

NICE NG88 provides evidence-based guidance for diagnosing and managing PCOS in UK clinical practice, improving patient outcomes and standardising care.

NICE CG156 provides evidence-based guidance on diagnosing and treating infertility, helping UK clinicians deliver consistent, effective fertility care.

NICE NG73 provides evidence-based guidance on diagnosing and managing endometriosis, helping UK clinicians improve patient outcomes and reduce diagnostic delays.

NICE NG23 provides evidence-based guidance on diagnosing and managing menopause, helping UK clinicians optimize treatment and improve women's health outcomes.

NICE NG303 provides evidence-based guidance on diagnosing and managing testicular cancer, improving treatment outcomes and standardizing care across UK health…

NICE CG1097 provides evidence-based guidance on diagnosing and treating erectile dysfunction, helping UK clinicians deliver effective patient care and improve…

BSSM guidelines standardize UK diagnosis and treatment of male testosterone deficiency, ensuring consistent clinical practice and optimal patient outcomes across…

NICE CG97 guides assessment and management of male lower urinary tract symptoms, improving diagnosis accuracy and treatment outcomes across UK…

NG131 provides evidence-based guidance on prostate cancer diagnosis and management, ensuring UK clinicians deliver consistent, high-quality, and cost-effective care.

NICE PH33 guides increasing HIV testing uptake to identify undiagnosed cases early, improving patient outcomes and reducing transmission in UK…

NICE NG188 provides guidance on diagnosing and managing long COVID symptoms in UK patients, helping clinicians deliver consistent, evidence-based care.

NICE NG33 provides evidence-based TB diagnosis, treatment, and management guidance for UK clinicians, ensuring consistent, effective care across all settings.

NICE NG141 guides UK clinicians on appropriate antibiotic selection for cellulitis and erysipelas, reducing unnecessary prescribing and improving patient outcomes.

NICE CG191 provides evidence-based guidance for diagnosing and managing pneumonia in adults, helping UK clinicians improve patient outcomes and reduce…

NICE NG112 provides evidence-based guidance on diagnosing and treating urinary tract infections in adults, improving clinical outcomes and reducing inappropriate…

NICE NG51 provides evidence-based guidance on identifying, diagnosing and promptly treating sepsis to reduce mortality and improve patient outcomes across…

NICE NG104 provides evidence-based guidance on diagnosing and managing acute and chronic pancreatitis, improving patient outcomes and standardising UK clinical…

NICE CG141 guides diagnosis, risk assessment and management of upper GI bleeding in adults, improving outcomes and standardising UK clinical…

NICE NG50 provides evidence-based guidance on assessing and managing cirrhosis in adults, helping UK clinicians improve patient outcomes and standardise…

NICE NG133 provides evidence-based guidance on diagnosing and managing chronic hepatitis B, helping UK clinicians optimize patient care and reduce…

NICE NG20 provides evidence-based guidance on diagnosing and managing coeliac disease, ensuring UK clinicians deliver consistent, quality care and improve…

NICE CG61 provides evidence-based guidance for diagnosing and managing IBS in adults, standardizing UK clinical practice and improving patient care…

NICE CG177 provides evidence-based osteoarthritis management guidance, helping UK clinicians deliver consistent, effective patient care and improve outcomes.

BSR guidelines provide evidence-based recommendations for diagnosing and managing systemic lupus erythematosus, improving clinical outcomes and standardising care across UK…

NICE NG65 provides evidence-based guidance for diagnosing and treating axial spondyloarthritis, helping UK clinicians improve patient outcomes and standardise care.

NICE NG65 provides evidence-based guidance on diagnosing and treating psoriatic arthritis, helping UK clinicians improve patient outcomes through standardised care…

NICE NG219 provides evidence-based guidance on diagnosing and managing gout, helping UK clinicians improve patient outcomes and reduce recurrent attacks…

NICE CG146 guides clinicians on identifying osteoporosis risk and preventing fragility fractures through evidence-based assessment and treatment in UK practice.

NICE CG31 guides assessment and treatment of OCD and BDD, reducing harmful delays and improving patient outcomes through evidence-based UK…

NICE NG225 provides evidence-based guidance on assessing, managing, and preventing self-harm recurrence, essential for UK clinicians delivering consistent, effective care.

NICE NG69 provides evidence-based guidance on recognizing and treating eating disorders, essential for UK clinicians to improve patient outcomes and…

NICE NG116 provides evidence-based guidance on diagnosing and treating PTSD in UK patients, improving clinical outcomes and standardising care across…

NICE NG87 provides evidence-based guidance on diagnosing and managing ADHD across all ages, ensuring consistent, high-quality care throughout the UK.

NICE NG185 provides UK clinicians with evidence-based guidance on diagnosing and treating bipolar disorder, improving patient outcomes and care consistency.

NICE NG224 provides evidence-based guidance on diagnosing and treating psychosis and schizophrenia in adults, essential for consistent, quality care across…

NICE CG109 guides UK clinicians in diagnosing and managing causes of fainting, preventing unnecessary investigations and improving patient safety outcomes.

NICE NG42 provides evidence-based guidance on diagnosing and managing motor neurone disease, enabling UK clinicians to deliver consistent, high-quality care.

NICE NG236 guides stroke rehabilitation management in adults, improving recovery outcomes and standardizing evidence-based care across UK health services.

NICE CG150 provides evidence-based guidance for diagnosing and managing headaches in children over twelve and adolescents, ensuring consistent UK clinical…

NG220 provides evidence-based guidance for diagnosing, treating, and managing multiple sclerosis in adults, helping UK clinicians deliver consistent, high-quality patient…

NG71 provides UK clinicians with evidence-based guidance on diagnosing and managing Parkinson's Disease in adults, ensuring consistent, high-quality patient care.

NICE NG36 provides evidence-based guidance for diagnosing and managing head and neck cancers, ensuring UK clinicians deliver consistent, high-quality care…

NICE NG167 provides evidence-based cervical cancer diagnosis and management guidelines, ensuring UK clinicians deliver consistent, high-quality care and optimal patient…

NICE NG52 provides evidence-based guidance on diagnosing and treating non-Hodgkin's lymphoma, helping UK clinicians deliver standardised, high-quality patient care.

NICE NG35 provides evidence-based guidance on diagnosing and managing multiple myeloma, ensuring consistent, high-quality care across UK healthcare services.

NICE NG2 provides evidence-based guidance on diagnosing and treating bladder cancer, ensuring consistent, high-quality patient care across UK healthcare services.

NG83 provides evidence-based guidance on diagnosing and treating oesophageal and gastric cancers, standardising UK clinical practice and improving patient outcomes.

NICE NG85 provides evidence-based guidance on diagnosing and managing pancreatic cancer in adults, ensuring UK clinicians deliver consistent, high-quality patient…

NICE NG14 provides evidence-based guidelines for diagnosing and treating melanoma in the UK, ensuring consistent, high-quality patient care across the…

NICE NG241 provides evidence-based guidance on recognizing ovarian cancer symptoms and initial management, improving early diagnosis and patient outcomes across…

NICE NG131 provides evidence-based prostate cancer diagnosis and management guidance, ensuring UK clinicians deliver consistent, high-quality, patient-centered care nationwide.

NICE NG151 provides evidence-based guidance on diagnosing and treating colorectal cancer, essential for standardizing care across UK healthcare services.

TA1026 recommends tirzepatide as a weight-loss treatment for overweight/obese adults, guiding NHS prescribing decisions and improving patient access to effective…

NICE TA875 evaluates semaglutide's clinical and cost-effectiveness for treating overweight and obesity in adults, guiding UK prescribing decisions.

NICE NG3 provides evidence-based guidance on gestational diabetes screening, diagnosis and management to improve maternal and fetal outcomes across UK…

NICE NG19 provides evidence-based guidance on preventing and managing diabetic foot complications, reducing amputations and improving patient outcomes in UK…

NICE NG49 provides evidence-based guidance for diagnosing and managing non-alcoholic fatty liver disease, helping UK clinicians reduce serious liver complications…

NICE CG189 provides evidence-based guidance on identifying, assessing, and managing obesity in UK clinical practice, improving patient outcomes and reducing…

Dupilumab guidance for moderate-to-severe atopic dermatitis in UK patients; clarifies NHS funding eligibility and treatment criteria for clinicians.

Mepolizumab reduces severe asthma attacks in patients with high eosinophil counts, offering NHS-approved treatment when standard therapies fail.

NICE NG117 provides evidence-based guidance for diagnosing and managing non-cystic fibrosis bronchiectasis, improving UK clinical outcomes and standardising care.

NICE NG202 provides evidence-based guidance for diagnosing and managing sleep apnoea in UK patients, improving outcomes and reducing untreated disease…

NICE NG163 guides UK clinicians on diagnosing and managing idiopathic pulmonary fibrosis, improving patient outcomes through standardised evidence-based care pathways.

TA773 approves Empagliflozin for heart failure with reduced ejection fraction, offering clinicians an effective treatment option to improve patient outcomes…

TA631 evaluates TAVI versus surgical replacement for aortic valve disease, guiding UK clinicians on cost-effective treatment selection for patients.

NICE NG128 provides evidence-based guidance on diagnosing strokes and TIAs and initial management, essential for UK clinicians to optimize patient…

NICE CG147 provides evidence-based guidance on diagnosing and managing peripheral arterial disease, helping UK clinicians improve patient outcomes and reduce…

NICE NG238 guides cardiovascular disease risk assessment and prevention strategies, helping UK clinicians identify high-risk patients and reduce heart disease…

NG158 guides diagnosis, treatment, and prevention of blood clots in veins, reducing patient harm and improving outcomes across UK healthcare…

NICE CG126 guides UK clinicians on diagnosing and managing stable angina, improving patient outcomes and standardising care quality.

NICE NG106 provides evidence-based guidance on diagnosing and managing heart failure, helping UK clinicians deliver consistent, high-quality patient care.

Source: NICEView full guideline on NICE ↗ See full guideline on the NICE website. ClinicaliQ Editorial Note: Sourced and indexed…

NICE NG222 (2022) significantly updated depression guidance, moving away from the stepped-care severity model to a more person-centred approach offering…

NICE CG113 covers the management of generalised anxiety disorder and panic disorder in primary and secondary care settings.

NICE NG97 provides comprehensive guidance on the assessment, diagnosis, management and support of people with dementia and their carers.

NICE NG217 covers the diagnosis and management of epilepsy across all ages, including antiseizure medication selection, surgical referral, and special…

NICE NG101 covers the diagnosis and management of early and locally advanced breast cancer including surgery, radiotherapy, systemic therapy, and…

NICE NG122 covers the diagnosis, staging, and treatment of lung cancer including NSCLC and SCLC, with guidance on targeted therapy…

NICE NG100 covers the management of rheumatoid arthritis including conventional DMARD therapy, biologic therapy, treat-to-target principles, and monitoring.

NICE NG130 covers the management of ulcerative colitis including induction of remission, maintenance therapy, and the use of biologic agents.

NICE NG129 covers the management of Crohn's disease including induction of remission with corticosteroids and enteral nutrition, maintenance therapy, and…

NICE NG15 provides guidance for healthcare organisations on implementing antimicrobial stewardship programmes to optimise antibiotic prescribing and combat antimicrobial resistance.

NICE NG136 provides comprehensive guidance on the identification, assessment, and treatment of hypertension in adults. Updated 2023 to include ambulatory…

NICE NG185 covers the management of acute coronary syndromes including NSTEMI and unstable angina, with updated recommendations on antiplatelet therapy,…

NICE NG196 covers the diagnosis and management of atrial fibrillation including stroke risk assessment, anticoagulation, and rate/rhythm control strategies.

NICE NG28 (updated 2024) provides updated guidance on management of type 2 diabetes including revised treatment algorithm with emphasis on…

NICE NG17 covers the management of type 1 diabetes, including insulin regimens, blood glucose monitoring technologies, and management of complications.

NICE NG115 provides comprehensive guidance on the diagnosis and management of COPD including spirometry, inhaler therapy, pulmonary rehabilitation, and exacerbation…

NICE NG80 provides guidance on the diagnosis and management of asthma in adults and children, including updated stepwise treatment ladder…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICE View full guideline on NICE See full guideline on NICE website. ClinicaliQ Editorial Note: Sourced from NICE. Always…

Source: NICEView full guideline on NICE ↗ See full guideline on the NICE website. ClinicaliQ Editorial Note: Sourced and indexed…