Transplanted pig kidney works in US man’s body for record 271 days

• Xenotransplantation milestone: A pig kidney functioned successfully in a human recipient for 271 days—the longest recorded survival to date—demonstrating progress towards addressing donor organ shortage.
• Bridge therapy potential: This case shows xenotransplantation could serve as a viable temporary solution for patients with end-stage renal disease awaiting human kidney transplants, potentially reducing mortality on waiting lists.
• Immunosuppression refinement needed: The procedure required intensive immunosuppressive regimens; further research is essential to establish optimal drug protocols, long-term safety profiles, and patient selection criteria before wider clinical implementation.

A man has lived for a record nine months with a transplanted pig kidney while waiting for a human transplant.

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