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Trial Collections

Themed entry points into Trial Radar

These collections group high-interest trial areas with nearby guidelines, Drug Science explainers and clinical briefs, so you can move from headline results to practical context without hopping across archives.

6 curated themes 457 total trials indexed Trial Radar plus linked clinical context

Collections

Use these to orient quickly in a topic area, then continue into the full trial archive or the relevant specialty hub.

Cardio-Renal

Cardiovascular, kidney and metabolic outcomes

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A practical route into outcomes trials spanning heart failure, chronic kidney disease and diabetes-driven cardiovascular risk.

Recruiting NCT07516496

Metabolic Phenotyping in vEDS

Metabolic Phenotyping in vEDS is Recruiting • Phase not applicable • Cardiology / Cardiovascular • NCT07516496. This research study will investigate whether…

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Phase III Recruiting NCT06200207

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation is Recruiting • Phase…

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Phase II Recruiting NCT06111586

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS) is Recruiting…

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Related Guideline EMA Guideline on Clinical Investigation of Medicinal Products for Heart Failure
Drug Science HMG-CoA Reductase — Statins
Clinical Brief New light shed on who benefits most from weight-loss jabs
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Respiratory

Airways, biologics and exacerbation prevention

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Trials shaping asthma, COPD and severe airways disease management, from biologics to exacerbation reduction strategies.

Recruiting NCT06891755

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung – Study 3

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung – Study 3 is Recruiting • Phase not applicable • Respiratory / COPD…

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Phase III Recruiting NCT05595642

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease is Recruiting • Phase III • Respiratory / COPD /…

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Phase III Recruiting NCT06238622

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With…

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Related Guideline Digital technologies for applying algorithms to spirometry to support asthma and COPD diagnosis in primary care and community diagnostic centres: early-use assessment
Drug Science CFTR Modulation
Clinical Brief File on 4 Investigates
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Immunology

Inflammation, biologics and immune pathways

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Immune-mediated disease research across rheumatology, dermatology and inflammatory pathways with clinically useful mechanism context.

Phase II Recruiting NCT07015983

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) is Recruiting…

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Recruiting NCT05507723

Tight Control of Gouty Arthritis Compared to Usual Care

Patient-led urate monitoring with smartphone support reduces gout flares compared to standard treatment approaches.

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Phase III Recruiting NCT06461897

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to…

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Related Guideline Subcutaneous spesolimab 1-ml formulation for preventing generalised pustular psoriasis flares in people 12 years and over (terminated appraisal)
Drug Science S1P Receptor Modulation — MS/IBD
Clinical Brief Prince William praises £20m milestone for Bowelbabe fund
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Oncology

Checkpoint, targeted and precision oncology trials

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A fast entry point into oncology trial activity, combining registry-linked studies with the supporting drug science and related clinical briefings.

Phase I Recruiting NCT06188520

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With…

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Phase I Recruiting NCT07181161

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer is Recruiting • Phase I • Oncology •…

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Phase I Active Not Recruiting NCT05571839

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors is Active Not Recruiting • Phase I • Oncology • NCT05571839.…

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Related Guideline EMA Reflection Paper on Extrapolation of Efficacy in Oncology
Drug Science BRAF/MEK Pathway — Melanoma
Clinical Brief Prince William praises £20m milestone for Bowelbabe fund
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Neuro / Mental Health

Neurology and mental health evidence watch

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Trials and linked clinical context for neurology and psychiatry where practice is moving quickly and clinicians need concise orientation.

Recruiting NCT04165109

Trial-Ready Cohort-Down Syndrome (TRC-DS)

Trial-Ready Cohort-Down Syndrome (TRC-DS) is Recruiting • Phase not applicable • Neurology • NCT04165109. The purpose of the Trial-Ready Cohort - Down…

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Phase III Recruiting NCT07174310

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson’s Disease

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson’s Disease is Recruiting • Phase…

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Phase I Recruiting NCT07234942

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer’s Disease (eAD)

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer’s Disease (eAD) is Recruiting…

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Related Guideline 2022 EAN/EFNS Guidelines on Dementia Diagnosis and Management
Drug Science S1P Receptor Modulation — MS/IBD
Clinical Brief Escaping the manosphere
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Infectious Disease

Infection, antimicrobial and outbreak-linked research

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Current infectious disease trials with the nearby clinical updates and guidance needed to place them in real-world practice.

Recruiting NCT05993442

Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU.

Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU. is Recruiting • Phase not…

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Recruiting NCT07300254

Treponemal Shedding, Load, and Viability, in Women and Men-who-have-sex-with-women-only With Early Infectious Syphilis: Implications for Transmission

Treponemal Shedding, Load, and Viability, in Women and Men-who-have-sex-with-women-only With Early Infectious Syphilis: Implications for Transmission is Recruiting • Phase not applicable…

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Phase III Recruiting NCT07128550

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide is Recruiting • Phase III •…

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Related Guideline 2022 ESCMID Guidelines on Candidaemia and Invasive Candidiasis
Drug Science IL-6 Signalling
Clinical Brief Hepatitis C infections in people who inject drugs continue to fall
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