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Clinical Trial ● Currently Recruiting Phase III NCT06129864

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy — Recruiting • Phase III •…

📅 24 Jun 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT06129864
Start
2023-12-14
Completion
2030-04-17
ClinicaliQ Trial Snapshot
  • A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy — Recruiting • Phase III • NCT06129864.
  • Trial testing a new drug (volrustomig) versus monitoring in head and neck cancer patients after chemoradiotherapy.

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What This Trial Is Studying

The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT). Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma Interventions: volrustomig Lead Sponsor: AstraZeneca Planned Enrollment: 1145 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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