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Clinical Trial Active — Not Recruiting Phase III NCT05984277

A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.

A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer. — Active Not Recruiting • Phase III •…

📅 28 Jul 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05984277
Start
2023-10-24
Completion
2029-02-28
ClinicaliQ Trial Snapshot
  • A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer. — Active Not Recruiting • Phase III • Oncology • NCT05984277.
  • New drug volrustomig plus chemotherapy compared with pembrolizumab plus chemotherapy for advanced lung cancer with low PD-L1 levels.

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What This Trial Is Studying

The purpose of eVOLVE-Lung02 is to test the effectiveness (efficacy) and measure the safety of volrustomig in combination with chemotherapy compared with pembrolizumab in combination with chemotherapy as 1L treatment in participants with mNSCLC in PD-L1 < 50%. Conditions: Metastatic Non-small Cell Lung Cancer Interventions: Volrustomig, Pembrolizumab, Carboplatin, Paclitaxel, Pemetrexed Lead Sponsor: AstraZeneca Planned Enrollment: 895 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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