- A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer — Active Not Recruiting • Phase III • Oncology • NCT05221840.
- Testing two immunotherapy combinations after chemotherapy and radiotherapy in advanced lung cancer patients.
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This is a Phase III, randomised, double-blind, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) in combination with oleclumab (MEDI9447) or durvalumab (MEDI4736) with monalizumab (IPH2201) in adults with locally advanced (Stage III), unresectable NSCLC, who have not progressed following platinum-based cCRT. Conditions: Non-Small Cell Lung Cancer Interventions: Durvalumab, Oleclumab, Monalizumab, Placebo Lead Sponsor: AstraZeneca Planned Enrollment: 1051 participants