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Clinical Trial ● Currently Recruiting Phase II NCT05646381

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis — Recruiting • Phase II • Cardiology /…

📅 15 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II
NCT ID
NCT05646381
Sponsor
Novartis Pharmaceuticals
Start
2024-03-07
ClinicaliQ Trial Snapshot
  • A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis — Recruiting • Phase II • Cardiology / Cardiovascular • NCT05646381.
  • Sponsor: Novartis Pharmaceuticals.

Verify eligibility, endpoints and current status on the original source registry before acting on this summary.

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  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in slowing the progression of calcific aortic valve stenosis.

Eligibility Snapshot
  • : * Male and female ≥50 to

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Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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