Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting Phase III NCT06881992

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism — Recruiting • Phase III • Diabetes / Metabolic • NCT06881992.

📅 17 Aug 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT06881992
Start
2025-04-16
Completion
2027-09
ClinicaliQ Trial Snapshot
  • A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism — Recruiting • Phase III • Diabetes / Metabolic • NCT06881992.
  • Study testing whether ersodetug added to standard treatment reduces low blood sugar episodes in patients with insulin-producing tumours.

Verify eligibility, endpoints and current status on the original ClinicalTrials.gov registry before acting on this summary.

Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The objectives of this study are to evaluate the glycemic efficacy, safety, and tolerability of ersodetug as add-on to standard of care (SOC) therapy for treatment of hypoglycemia in patients with Tumor Hyperinsulinism (Tumor HI). Conditions: Tumor Hyperinsulinism (Tumor HI) Interventions: Ersodetug Lead Sponsor: Rezolute Planned Enrollment: 16 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Clinical Brief
Insulin pumps and continuous glucose monitoring (CGM) equipment: guidance for users on reporting suspected adverse incidents and safety concerns to the MHRA’s Yellow Card scheme
Diabetes / Metabolic · MHRA · 24 Oct 2024
We ask healthcare professionals to support new guidance for users of diabetes management equipment, their families, care givers and representatives. This update…
View brief →
Guideline
Insulin efsitora alfa for treating type 2 diabetes
Diabetes / Metabolic · 16 Oct 2026
Insulin efsitora alfa is recommended as a treatment option for type 2 diabetes and should be considered within NICE guidance criteria—confirm patient…
View guideline →
Guideline
Gestational Diabetes: Diagnosis and Treatment (NICE NG3)
Diabetes / Metabolic · 27 Mar 2026
Perform a 2-hour 75 g OGTT between 24–28 weeks in women with GDM risk factors; diagnose GDM if fasting glucose ≥5.6 mmol/L…
View guideline →
Podcast
GLP-1 Agonists: Semaglutide, Tirzepatide and the Cardiovascular Revolution
Diabetes / Metabolic · 00:15:32 · 03 Apr 2026
GLP-1 receptor agonists mimic gut-derived GLP-1: they increase glucose-dependent insulin release, suppress glucagon and slow gastric emptying. Semaglutide is a once-weekly GLP-1…
Listen →
Podcast
SGLT2 Inhibitors: From Glycaemia to Heart Failure and Chronic Kidney Disease
Diabetes / Metabolic · 00:14:06 · 03 Apr 2026
SGLT2 inhibitors block glucose reabsorption in the proximal renal tubule, causing glycosuria with effects that extend beyond HbA1c lowering. DAPA-HF and EMPEROR-Reduced…
Listen →
Guideline
Semaglutide for Managing Overweight and Obesity (NICE TA875)
Diabetes / Metabolic · 27 Mar 2026
Initiate semaglutide only in specialist obesity services or via shared care with clear primary-secondary care protocols for adults with BMI ≥30 kg/m²…
View guideline →