ClinicaliQ Trial Snapshot
- A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction — Recruiting • Phase II • Cardiology / Cardiovascular • NCT05887271.
- What is being tested: A low-energy diet intervention to improve functional status and symptoms in patients with heart failure with preserved ejection fraction (HFpEF), a condition where the heart cannot relax properly despite maintaining normal pumping strength.
- Patient eligibility overview: The trial enrolls patients with HFpEF who typically have comorbid obesity and/or type 2 diabetes, representing a substantial proportion of the HFpEF population in clinical practice.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Heart failure with preserved ejection fraction (HFpEF) is a common and serious complication of obesity and type 2 diabetes (T2D). HFpEF occurs when the heart muscle unable to relax efficiently to pump the blood around the body. This leads to fluid build-up, breathlessness and inability to tolerate physical exertion. People who develop HFpEF do less well because treatment options are limited. Pilot data in patients with obesity and diabetes and a small number of patients with HFpEF have shown improvements in exercise capacity and reversal of changes in the heart…
Eligibility Snapshot
- : 1. Established clinical diagnosis of heart failure with preserved ejection fraction HFpEF (EF>45%) made by a cardiologist or a primary care physician with heart failure expertise, or a heart failure nurse 2. Clinically stable for ≥ 3 months (no admissions to hospital) 3. Obesity (BMI ≥30kg/m2 if white European or ≥27kg/m2 if Asian, Middle Eastern or Black ethnicity) 4. Age ≥18
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.