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Clinical Trial Active — Not Recruiting Phase I NCT04910568

A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma

A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma — Active Not Recruiting • Phase I • NCT04910568.

📅 17 Aug 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT04910568
Start
2021-07-26
Completion
2028-12-21
ClinicaliQ Trial Snapshot
  • A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma — Active Not Recruiting • Phase I • NCT04910568.
  • Early-stage trial testing a new antibody drug (cevostamab) alone or combined with existing treatments for hard-to-treat multiple myeloma.

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What This Trial Is Studying

This Phase Ib, multicenter, open-label study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cevostamab monotherapy, cevostamab plus pomalidomide and dexamethasone (Pd) or cevostamab plus daratumumab and dexamethasone (Dd) which will be administered to participants with relapsed or refractory multiple myeloma (R/R MM) via intravenous (IV) infusion. Conditions: Multiple Myeloma Interventions: Cevostamab, Tocilizumab, Pomalidomide, Daratumumab, Dexamethasone Lead Sponsor: Genentech, Inc. Planned Enrollment: 186 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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