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Clinical Trial Active — Not Recruiting Phase II NCT06718101

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis — Active Not Recruiting…

📅 04 Aug 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase II
NCT ID
NCT06718101
Start
2024-12-19
Completion
2027-05
ClinicaliQ Trial Snapshot
  • A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis — Active Not Recruiting • Phase II • Dermatology • NCT06718101.
  • Trial testing lutikizumab injections alone and in combination for moderate to severe eczema over 52 weeks.

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What This Trial Is Studying

Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. The purpose of this study is to evaluate the clinical efficacy and safety of single therapies and/or combination therapies for moderate to severe AD through multiple substudies. This study will consist of multiple substudies. Substudy 1 will have a randomized, open-label period 1 followed by a lutikizumab treatment period 2 enrolling 80 participants at a 1 to 1 ratio. In Substudy 1, participants will receive subcutaneous (SC) injections of lutikizumab…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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Related Clinical Intelligence

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Guideline
Atopic Eczema in Under 12s: Diagnosis and Management (NICE NG190)
Dermatology · 27 Mar 2026
Diagnose atopic eczema clinically based on itching, typical morphology and distribution, onset before age 2 years, and history of dry skin or…
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This NICE publication is marked as a terminated appraisal, so it functions as a status notice rather than an active treatment recommendation…
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Clinical Brief
Our skin is falling off and no-one can tell us why
Dermatology · BBC Health · 29 Mar 2026
Topical Steroid Withdrawal: Key Clinical Takeaways TSW is now subject to formal UK research: Growing social media documentation of cases has prompted…
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Hundreds contact BBC about mystery skin condition ‘hell’ – but doctors can’t agree it exists
Dermatology · BBC Health · 10 Apr 2026
Doctors remain divided on whether a severe skin condition reported by hundreds of patients represents extreme eczema or a distinct entity called…
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Guideline
Hidradenitis Suppurativa: Assessment and Management (NICE NG73)
Dermatology · 27 Mar 2026
Diagnose hidradenitis suppurativa clinically based on recurrent painful nodules, abscesses, sinus tracts, and scars localised to intertriginous areas (axillae, groin, inframammary folds),…
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