Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting Phase III NCT07753993

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease. — Recruiting • Phase III • Diabetes / Metabolic • NCT07753993.

📅 09 Sep 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT07753993
Sponsor
AstraZeneca
Start
2026-08-21
ClinicaliQ Trial Snapshot
  • A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease. — Recruiting • Phase III • Diabetes / Metabolic • NCT07753993.
  • Sponsor: AstraZeneca.

Verify eligibility, endpoints and current status on the original source registry before acting on this summary.

Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compared with placebo in participants with CKD with and without T2DM who are on background SGLT2i (dapagliflozin) as GDMT and other SoC treatments for CKD.

Eligibility Snapshot
  • : * Adults with confirmed CKD; UACR ≥30 mg/g and eGFR ≥20 mL/min/1.73 m² within specified ranges. * On stable, patient maximum tolerated, labeled daily dose of ACEI or ARB for ≥4 weeks at least 28 days before screening.

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Webinar
SGLT2 Inhibitors: From Glycaemia to Heart Failure and Chronic Kidney Disease
Diabetes / Metabolic · 0.5 · 05 Apr 2026
recorded webinar focused on SGLT2 Inhibitors in diabetes and metabolic medicine. Use the recording with the slide outline to review mechanism, evidence,…
Watch webinar →
Podcast
SGLT2 Inhibitors: From Glycaemia to Heart Failure and Chronic Kidney Disease
Diabetes / Metabolic · 00:14:06 · 03 Apr 2026
SGLT2 inhibitors block glucose reabsorption in the proximal renal tubule, causing glycosuria with effects that extend beyond HbA1c lowering. DAPA-HF and EMPEROR-Reduced…
Listen →
CPD
NICE NG28: Type 2 Diabetes in Adults — 2024 Update
Diabetes / Metabolic · 1.5 CPD hours · 25 Mar 2026
Apply NICE NG28 updates to type 2 diabetes treatment sequencing, including when SGLT2 inhibitors or GLP-1 receptor agonists should be prioritised. Match…
Complete CPD →
Clinical Brief
Obesity cases rising fastest in young adults
Diabetes / Metabolic · BBC Health · 24 Jun 2026
Obesity prevalence is increasing most rapidly among young adults, driven by cost of living pressures, pandemic-related behavioural changes, and increased availability of…
View brief →
Guideline
Type 2 Diabetes in Adults: Management (NICE NG28, 2024 Update)
Diabetes / Metabolic · 25 Mar 2026
Initiate metformin as first-line therapy in type 2 diabetes unless eGFR
View guideline →
Guideline
Type 1 Diabetes in Adults: Diagnosis and Management (NICE NG17)
Diabetes / Metabolic · 25 Mar 2026
Offer multiple daily injection (MDI) basal-bolus insulin regimen as first-line treatment for all adults with type 1 diabetes, with continuous subcutaneous insulin…
View guideline →