- Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma — Active Not Recruiting • Phase II • NCT05004064.
- Acalabrutinib plus rituximab showed promise as a gentler first-line treatment option for elderly or frail patients with mantle cell lymphoma.
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This is a phase II, single-arm, open-label, multicentre study of acalabrutinib and rituximab for elderly or frail patients with previously untreated mantle cell lymphoma. Conditions: Mantle Cell Lymphoma Interventions: Acalabrutinib, Rituximab Lead Sponsor: University College, London Planned Enrollment: 48 participants