ClinicaliQ Trial Snapshot
- Chemo Brain Prehab Project — Recruiting • Non-phase study • Oncology • NCT07341217.
- What is being tested: A prehabilitation (pre-treatment) intervention designed to prevent or mitigate chemotherapy-induced cognitive impairment ("chemo brain") in colorectal cancer patients receiving fluorouracil, capecitabine, or oxaliplatin-based chemotherapy.
- Patient eligibility overview: Colorectal cancer patients in the North West region scheduled to receive chemotherapy, with particular focus on a population experiencing 37% higher incidence rates than the national average.
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- Quick orientation before opening the registry record.
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What This Trial Is Studying
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin. A side effect of these drugs is loss of memory, forgetfulness, and general brain fog, which can persist for months after the end of treatment. These symptoms are collectively known as 'chemo-brain'. An existing prehabilitation intervention that has been previously developed will be used, which increases fitness and reduces hospital length of stay in colorectal cancer surgery patients, to try to improve the symptoms of chemo-brain in…
Eligibility Snapshot
- : * Individuals with stage II or III colorectal cancer undergoing chemotherapy with fluorouracil, capecitabine, or oxaliplatin. * Aged 60-85 years old. * Fluent in English * Male and female participants * Not engaged in structured exercise training* within the six months before providing consent.
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.