- Comparative Evaluation of Sustained meChanical AsPiration Thrombectomy and no Thrombus Modification for Pre-stent Thrombus bUrden Reduction in Patients With Acute Myocardial Infarction Study: the CAPTURE AMI Study — Recruiting • Phase II • Cardiology / Cardiovascular • NCT07687576.
- Treatment being tested: Sustained mechanical aspiration thrombectomy versus standard percutaneous coronary intervention (PCI) without thrombus modification in STEMI patients with angiographically confirmed high thrombus burden before stent placement.
- Patient eligibility overview: Adults aged ≥18 years presenting with acute ST-elevation myocardial infarction who are undergoing primary PCI and have documented significant thrombus burden on coronary angiography.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
The CAPTURE AMI trial is an investigator-initiated, single-centre, two-arm, randomised controlled trial. Patients aged ≥ 18 years who present with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) will be enrolled after angiographic evidence of a high thrombus burden (TIMI thrombus grade ≥ 4) and meeting the inclusion criteria laid out in section 9.2 will be 1:1 randomised to receive either standalone PCI (Arm 1) or adjunct sustained mechanical thrombectomy + PCI (Arm 2). The CAPTURE AMI study will enrol specifically patients with: A. Evidence of high thrombus…
- : * Primary PCI patient with ST elevation myocardial infarction * Angiographic criteria: * TIMI 0/1 flow at presentation * Angiographic thrombus score ≥ 4 * Vessel diameter at site of occlusion ≥ 3.0mm (determined by coronary angiography)
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.