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Clinical Trial ● Currently Recruiting NCT05945043

Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion

Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion — Recruiting • Respiratory / COPD / Asthma • NCT05945043.

📅 04 Jun 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
NCT ID
NCT05945043
Sponsor
Guy's and St Thomas' NHS Foundation Trust
Start
2023-11-15
ClinicaliQ Trial Snapshot
  • Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion — Recruiting • Respiratory / COPD / Asthma • NCT05945043.
  • What is being tested: The study investigates how removing fluid from around the lungs (thoracocentesis) affects neural respiratory drive—the brain's signal to breathe—in patients with unilateral pleural effusions causing breathlessness.
  • Patient eligibility overview: The trial recruits patients with one-sided pleural effusions who experience breathlessness and require therapeutic fluid drainage as part of their clinical management.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management.

Eligibility Snapshot
  • : * Age 18 years or above * Has a unilateral pleural effusion AND 1. require thoracocentesis OR 2. chest drain insertion (main study only) OR 3. has an IPC in situ (main study only)

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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