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Clinical Trial ● Currently Recruiting Non-phase study NCT06165510

Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation

Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT06165510.

📅 20 May 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Non-phase study
NCT ID
NCT06165510
Sponsor
Barts & The London NHS Trust
Start
2024-08-02
ClinicaliQ Trial Snapshot
  • Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT06165510.
  • What is being tested: Convergent ablation (combining epicardial and endocardial approaches) plus left atrial appendage isolation using the LARIAT procedure, compared to standard endocardial catheter ablation alone in long-standing persistent atrial fibrillation.
  • Patient eligibility overview: Adults with long-standing persistent atrial fibrillation (typically AF duration >1 year, refractory to antiarrhythmic drugs or cardioversion) who are candidates for invasive rhythm control procedures.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).

Eligibility Snapshot
  • : * Age > 18 years; < 80 years * Persistent AF > 1-year duration * Left atrium size < 6cm * Pts should be able to provide written informed consent.

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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