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Clinical Trial Active — Not Recruiting Non-phase study NCT05492110

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction.

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. — Active Not Recruiting • Non-phase study • Cardiology / Cardiovascular •…

📅 12 Aug 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Non-phase study
NCT ID
NCT05492110
Start
2023-04-17
Completion
2026-08-04
ClinicaliQ Trial Snapshot
  • Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. — Active Not Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT05492110.
  • A device inserted into the coronary sinus improves blood flow and symptoms in patients with chest pain despite normal coronary arteries.

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What This Trial Is Studying

To demonstrate the feasibility and efficacy of the CS Reducer for the treatment of patients with ischaemia and non-obstructed coronary arteries (INOCA) and coronary microvascular dysfunction (CMD) and through a nested mechanistic substudy investigate the physiological responses in the coronary microcirculation responsible for changes in myocardial perfusion. Conditions: Refractory Angina, Microvascular Angina, Microvascular Coronary Artery Disease, Coronary Disease, Angina Pectoris, INOCA (Ischemia With Non Obstructive Coronary Artery Disease), ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD) Interventions: Coronary sinus reducer, Sham Procedure, Invasive coronary physiology Lead Sponsor:…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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