Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting NCT04873258

Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease

Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease — Recruiting • Diabetes / Metabolic • NCT04873258.

📅 19 Aug 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
NCT ID
NCT04873258
Sponsor
Richmond Research Institute
Start
2019-09-27
ClinicaliQ Trial Snapshot
  • Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease — Recruiting • Diabetes / Metabolic • NCT04873258.
  • What is being tested: Development and validation of a non-invasive screening tool to predict metabolic dysfunction-associated steatotic liver disease (MASLD), potentially replacing the need for invasive liver biopsy diagnosis.
  • Patient eligibility overview: The study recruits adults with metabolic risk factors (obesity, type 2 diabetes, dyslipidaemia) and/or imaging evidence of liver steatosis, establishing baseline structural and functional liver parameters across disease severity.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

A generic screening study to establish structural and/or functional baselines of specific organs.

Eligibility Snapshot
  • : 1. Male or female volunteers aged ≥18 to ≤80 years at the date of signing the informed consent. 2. Willingness and ability to provide written, personally signed, and dated informed consent, in accordance with the latest ICH Good Clinical Practice (GCP) Guidelines and applicable regulations. 3. An understanding, ability and willingness to fully comply with project procedures and restrictions. For PART B only: 1. With a known history of MASLD as evidenced either of: 1. GP diagnosis on HCF 2. Documented Fibroscan or liver US demonstrating MASLD

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Guideline
Metabolic dysfunction-associated steatotic liver disease (MASLD): assessment and management
Diabetes / Metabolic · 06 Jul 2016
Assess all patients with MASLD using FIB-4 index or transient elastography to stratify fibrosis risk—those with advanced fibrosis require specialist hepatology referral…
View guideline →
Guideline
Non-Alcoholic Fatty Liver Disease: Assessment and Management (NICE NG49)
Diabetes / Metabolic · 27 Mar 2026
Use FIB-4 or NAFLD Fibrosis Score in primary care to stratify fibrosis risk in adults with metabolic risk factors (type 2 diabetes,…
View guideline →
Guideline
Teplizumab for delaying the onset of stage 3 type 1 diabetes in people 8 years and over with stage 2 type 1 diabetes
Diabetes / Metabolic · 09 Jul 2026
Teplizumab is recommended for people aged 8 years and over with stage 2 type 1 diabetes to delay progression to stage 3;…
View guideline →
Clinical Brief
More young women in their 20s are getting type 2 diabetes
Diabetes / Metabolic · BBC Health · 22 Jul 2026
Type 2 diabetes incidence is rising significantly in women aged in their 20s in England, requiring heightened clinical vigilance for early detection…
View brief →
Guideline
Semaglutide for Managing Overweight and Obesity (NICE TA875)
Diabetes / Metabolic · 27 Mar 2026
Initiate semaglutide only in specialist obesity services or via shared care with clear primary-secondary care protocols for adults with BMI ≥30 kg/m²…
View guideline →
Guideline
Type 1 Diabetes in Adults: Diagnosis and Management (NICE NG17)
Diabetes / Metabolic · 25 Mar 2026
Offer multiple daily injection (MDI) basal-bolus insulin regimen as first-line treatment for all adults with type 1 diabetes, with continuous subcutaneous insulin…
View guideline →