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Clinical Trial ● Currently Recruiting Non-phase study NCT03854071

Development of Novel Physiological CMR Methods in Health and Disease

Development of Novel Physiological CMR Methods in Health and Disease — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT03854071.

📅 25 Mar 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Non-phase study
NCT ID
NCT03854071
Sponsor
Sheffield Teaching Hospitals NHS Foundation Trust
Start
2018-07-30
ClinicaliQ Trial Snapshot
  • Development of Novel Physiological CMR Methods in Health and Disease — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT03854071.
  • Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them offer varied insight into cardiac physiological adaptation: passive leg raise, intra-venous fluid….
  • Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust.

Verify eligibility, endpoints and current status on the original source registry before acting on this summary.

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  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them offer varied insight into cardiac physiological adaptation: passive leg raise, intra-venous fluid challenge, pharmacological stressors and physical exercise stress test. Echocardiography, which is the mainstay for the non-invasive rest/stress assessment of the left ventricular (LV) haemodynamics has several limitations. Novel methods of CMR imaging allow to map intra-cardiac flow in three-dimension using novel flow acquisitions. These novel flow acquisitions are…

Eligibility Snapshot
  • : * Healthy Volunteers age 20 to 80, recruited from Sheffield Teaching Hospitals staff members * Patients age 20 to 80 with suspected or known heart disease (group 1 to 5) * Capable of giving written informed consent

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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