Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting Phase IV NCT07402707

Dosing of Steroids for Acute Asthma Given in the Emergency Department – a Pilot Randomised Feasibility Trial of Dexamethasone in Children

Dosing of Steroids for Acute Asthma Given in the Emergency Department – a Pilot Randomised Feasibility Trial of Dexamethasone in Children — Recruiting • Phase IV • Respiratory…

📅 23 Apr 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase IV
NCT ID
NCT07402707
Sponsor
Sheffield Children's NHS Foundation Trust
Start
2026-02-23
ClinicaliQ Trial Snapshot
  • Dosing of Steroids for Acute Asthma Given in the Emergency Department – a Pilot Randomised Feasibility Trial of Dexamethasone in Children — Recruiting • Phase IV • Respiratory / COPD / Asthma • NCT07402707.
  • What is being tested: A pilot feasibility trial comparing dexamethasone (single-dose steroid) versus standard oral steroids for treating acute asthma exacerbations in children presenting to emergency departments.
  • Patient eligibility overview: Children presenting to emergency departments with acute asthma attacks requiring oral steroid treatment; the trial assesses feasibility of recruitment, adherence, and outcome measurement in this population.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Steroids given by mouth are an important first line treatment for children presenting with asthma attacks. Dexamethasone is the steroid used in some emergency departments (EDs) because of the need for a single dose and as it is well tolerated. The dose of dexamethasone in treating asthma attacks is not clearly established. This study compares two different doses of dexamethasone in children presenting with an asthma attack. Investigators will compare the effect of two different doses in reducing the need for a repeat prescription of steroids for an asthma attack…

Eligibility Snapshot
  • : * Children aged 4-15 years (inclusive) presenting to the ED with an asthma exacerbation, where oral steroids are recommended by Trust/National guidelines. * Children whose parents/carers do not speak English will also be eligible provided they speak one of the common languages where an interpreter and Information Sheets are available (Slovakian, Arabic and Urdu).

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Guideline
Brensocatib for treating non-cystic fibrosis bronchiectasis in people 12 years and over (terminated evaluation)
Respiratory / COPD / Asthma · 25 Aug 2026
Evaluation terminated: Brensocatib for non-CF bronchiectasis is no longer under NICE appraisal—do not initiate new treatment pathways for this indication pending alternative…
View guideline →
Guideline
UK Achondroplasia Network’s consensus guideline for multidisciplinary care of children and young people with achondroplasia: NICE review
Respiratory / COPD / Asthma · 19 May 2026
Establish multidisciplinary team review at diagnosis and at key developmental stages (infancy, pre-school, school age, adolescence) to monitor for complications including spinal…
View guideline →
Clinical Brief
What is postpartum psychosis and why is it central in the Lindsay Clancy trial?
Respiratory / COPD / Asthma · BBC Health · 19 Aug 2026
Postpartum psychosis is a rare but severe psychiatric emergency occurring in 1-2 per 1,000 deliveries, characterised by delusions, hallucinations, and disorganised thinking…
View brief →
Clinical Brief
AI sleep data could provide one-week early warning of flu and COVID-19
Respiratory / COPD / Asthma · UKHSA · 03 Sep 2026
Sleep-tracking apps analysing cough patterns can detect flu and COVID-19 approximately one week before symptom onset, potentially enabling early intervention and isolation…
View brief →
Clinical Brief
Over one million children referred for mental healthcare – with anxiety the main reason
Respiratory / COPD / Asthma · BBC Health · 29 Jun 2026
Over one million children in England have been referred for mental healthcare, with anxiety as the leading presenting complaint, indicating a substantial…
View brief →
Clinical Brief
Why is postpartum psychosis central in the Lindsay Clancy trial?
Respiratory / COPD / Asthma · BBC Health · 20 Aug 2026
Postpartum psychosis is being presented as a key defence in a high-profile case, highlighting the serious mental health risks in the immediate…
View brief →