- Dosing of Steroids for Acute Asthma Given in the Emergency Department – a Pilot Randomised Feasibility Trial of Dexamethasone in Children — Recruiting • Phase IV • Respiratory / COPD / Asthma • NCT07402707.
- What is being tested: A pilot feasibility trial comparing dexamethasone (single-dose steroid) versus standard oral steroids for treating acute asthma exacerbations in children presenting to emergency departments.
- Patient eligibility overview: Children presenting to emergency departments with acute asthma attacks requiring oral steroid treatment; the trial assesses feasibility of recruitment, adherence, and outcome measurement in this population.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
Steroids given by mouth are an important first line treatment for children presenting with asthma attacks. Dexamethasone is the steroid used in some emergency departments (EDs) because of the need for a single dose and as it is well tolerated. The dose of dexamethasone in treating asthma attacks is not clearly established. This study compares two different doses of dexamethasone in children presenting with an asthma attack. Investigators will compare the effect of two different doses in reducing the need for a repeat prescription of steroids for an asthma attack…
- : * Children aged 4-15 years (inclusive) presenting to the ED with an asthma exacerbation, where oral steroids are recommended by Trust/National guidelines. * Children whose parents/carers do not speak English will also be eligible provided they speak one of the common languages where an interpreter and Information Sheets are available (Slovakian, Arabic and Urdu).
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.