ClinicaliQ Trial Snapshot
- Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS — Active Not Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT03094143.
- Early aortic valve surgery guided by heart scarring markers may improve outcomes in asymptomatic patients with severe stenosis.
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What This Trial Is Studying
Aortic stenosis is the most common valvular disease in the Western world. It is caused by progressive narrowing of the aortic valve leading to increased strain on the heart muscle which has to work increasingly hard to pump blood through the narrowed valve. Over time the heart muscle thickens to generate more force, but eventually the heart fails leading to death if the valve is not replaced with an operation. No medical treatments exist to stop or reverse the heart valve narrowing. Current clinical guidelines suggest that an operation should…