- Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) — Active Not Recruiting • Phase III • NCT05263934.
- Depemokimab was compared to mepolizumab for treating difficult-to-control EGPA in adults already on standard treatment.
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This study aims to investigate the efficacy and safety of depemokimab compared with mepolizumab in adults with relapsing or refractory EGPA receiving SoC therapy. Conditions: Eosinophilic Granulomatosis With Polyangiitis Interventions: Depemokimab, Mepolizumab, Placebo matching mepolizumab, Placebo matching depemokimab Lead Sponsor: GlaxoSmithKline Planned Enrollment: 163 participants