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Clinical Trial Active — Not Recruiting Phase III NCT05263934

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) — Active Not Recruiting • Phase III • NCT05263934.

📅 08 Jul 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05263934
Start
2022-07-14
Completion
2026-09-29
ClinicaliQ Trial Snapshot
  • Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) — Active Not Recruiting • Phase III • NCT05263934.
  • Depemokimab was compared to mepolizumab for treating difficult-to-control EGPA in adults already on standard treatment.

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What This Trial Is Studying

This study aims to investigate the efficacy and safety of depemokimab compared with mepolizumab in adults with relapsing or refractory EGPA receiving SoC therapy. Conditions: Eosinophilic Granulomatosis With Polyangiitis Interventions: Depemokimab, Mepolizumab, Placebo matching mepolizumab, Placebo matching depemokimab Lead Sponsor: GlaxoSmithKline Planned Enrollment: 163 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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