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Clinical Trial ● Currently Recruiting Phase III NCT07311850

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity — Recruiting • Phase III • Diabetes / Metabolic • NCT07311850.

📅 12 Jun 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT07311850
Start
2025-12-19
Completion
2027-09-21
ClinicaliQ Trial Snapshot
  • Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity — Recruiting • Phase III • Diabetes / Metabolic • NCT07311850.
  • MET097 injected once weekly helped adults with obesity or overweight lose weight over 64 weeks of treatment.

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What This Trial Is Studying

This study investigates the efficacy and safety of once weekly injectable MET097 in adult participants with obesity or overweight with weight-related comorbidities excluding T2D. This trial will last for a duration of 84 weeks. The primary endpoint will be assessed after 64 weeks of treatment with the secondary at 84 weeks. Conditions: Obesity and Overweight Interventions: MET097, Placebo Lead Sponsor: Pfizer Planned Enrollment: 3501 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Guideline
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Guideline
Tirzepatide for Managing Overweight and Obesity (NICE TA1026)
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Podcast
GLP-1 Agonists: Semaglutide, Tirzepatide and the Cardiovascular Revolution
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Guideline
Obesity: Identification, Assessment and Management (NICE CG189)
Diabetes / Metabolic · 27 Mar 2026
Use BMI thresholds to identify obesity (≥30 kg/m² in adults; ≥27.5 kg/m² in Asian populations) and offer structured first-line weight loss interventions…
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