- Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN) — Active Not Recruiting • Phase III • NCT06564142.
- Povetacicept reduced proteinuria and slowed kidney decline in adults with IgA nephropathy compared to placebo.
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The purpose of this study is to evaluate the efficacy of povetacicept in adult participants compared with placebo in reducing proteinuria and preserving renal function. Conditions: Immunoglobulin A Nephropathy Interventions: Povetacicept, Placebo (matched to Povetacicept) Lead Sponsor: Alpine Immune Sciences Inc, A Subsidiary of Vertex Planned Enrollment: 605 participants