- Fibrosis Associated Protein Inhibitor (FAPI) Radiotracer-based Imaging to Identify Fibrotic Intestinal Crohn’s Disease — Recruiting • Cardiology / Cardiovascular • NCT07152431.
- What is being tested: Fibrosis-associated protein inhibitor (FAPI) radiotracer imaging as a novel diagnostic tool to identify and characterise fibrotic strictures in Crohn's Disease patients, potentially enabling earlier detection of intestinal fibrosis before symptomatic complications develop.
- Patient eligibility overview: The trial targets adult Crohn's Disease patients with known or suspected fibrotic stricturing disease, including those with obstructive symptoms or previous imaging findings suggestive of intestinal fibrosis.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
Crohn's Disease (CD) is a chronic inflammatory condition that can affect any part of the intestine and currently has no cure. It affects 6.8 million people worldwide with UK healthcare costs in excess of £1 billion per year. Recent data suggests that the despite significant progress in treatments over the last 2 decades to help control disease, up to half of patients still develop progressive bowel scarring that require surgery and up to 70% needing surgery within 10-20 years from diagnosis. Unfortunately this is not a cure and some still…
- : * Crohn's disease with ileal involvement (including those with disease recurrence in the neo-terminal ileum) due to commence biologics.
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.