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Clinical Trial Active — Not Recruiting Phase I NCT05277051

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors — Active Not Recruiting • Phase I • Oncology • NCT05277051.

📅 25 Jun 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT05277051
Start
2022-03-22
Completion
2027-08-31
ClinicaliQ Trial Snapshot
  • First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors — Active Not Recruiting • Phase I • Oncology • NCT05277051.
  • New cancer drug GSK4381562 tested for first time in humans with advanced tumours to check safety and how the body processes it.

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What This Trial Is Studying

This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of remzistotug in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment options have been exhausted. Conditions: Neoplasms Interventions: Remzistotug, Dostarlimab, Belrestotug, Nelistotug, GSK5764227 Lead Sponsor: GlaxoSmithKline Planned Enrollment: 152 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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