- First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors — Active Not Recruiting • Phase I • Oncology • NCT05277051.
- New cancer drug GSK4381562 tested for first time in humans with advanced tumours to check safety and how the body processes it.
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This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of remzistotug in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment options have been exhausted. Conditions: Neoplasms Interventions: Remzistotug, Dostarlimab, Belrestotug, Nelistotug, GSK5764227 Lead Sponsor: GlaxoSmithKline Planned Enrollment: 152 participants