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Clinical Trial Active — Not Recruiting Phase I / Phase II NCT04083599

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors — Active Not Recruiting • Phase I / Phase II • Oncology • NCT04083599.

📅 08 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I / Phase II
NCT ID
NCT04083599
Start
2019-09-17
Completion
2025-12-30
ClinicaliQ Trial Snapshot
  • GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors — Active Not Recruiting • Phase I / Phase II • Oncology • NCT04083599.
  • GEN1042 antibody tested alone and combined with pembrolizumab, with or without chemotherapy, in patients with solid tumours.

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What This Trial Is Studying

The goal of this trial is to learn about the antibody GEN1042 when it is used alone and when it is used together with another antibody cancer drug, pembrolizumab (with or without chemotherapy), for treatment of participants with certain types of cancer. Conditions: Malignant Solid Tumor, Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Melanoma, Head and Neck Squamous Cell Carcinoma (HNSCC), Pancreatic Ductal Adenocarcinoma (PDAC) Interventions: GEN1042, Pembrolizumab, Cisplatin, Carboplatin, 5-FU, Gemcitabine, Nab paclitaxel, Pemetrexed, Paclitaxel Lead Sponsor: Genmab Planned Enrollment: 350 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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