- Granulocyte Transfusions After Umbilical Cord Blood Transplant — Active Not Recruiting • Non-phase study • Oncology • NCT05425043.
- Study testing whether white blood cell transfusions improve immune recovery and outcomes after cord blood stem cell transplant in children with leukaemia.
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Although most children with leukaemia are cured using drugs (chemotherapy) alone, for some children additional treatments are needed. Stem cell transplant can cure children where chemotherapy and other drugs have failed. In this case, the immune cells of the donor attack the leukaemia cells of the patient. Cord blood collected from the placenta of unrelated babies is often used as a donor cell source and appears to work well at controlling leukaemia and less likely to cause complications such as when the immune cells also mistakenly attack healthy tissues (called…