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Clinical Trial ● Currently Recruiting NCT07702825

Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity

Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity — Recruiting • Diabetes / Metabolic • NCT07702825.

📅 14 Jul 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
NCT ID
NCT07702825
Start
2026-03-06
Completion
2027-12
ClinicaliQ Trial Snapshot
  • Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity — Recruiting • Diabetes / Metabolic • NCT07702825.
  • GLP-1 drugs plus lifestyle changes versus lifestyle alone for weight loss and organ health improvement in obese teenagers.

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What This Trial Is Studying

The goal of this study is to quantify the body composition and organ fat distribution changes with obesity interventions in adolescents with severe obesity. The main question the investigators aim to answer is if there is improvement in organ health with weight loss intervention. The investigators will be comparing the degree of these changes between children being treated with GLP1 receptor agonists in addition to lifestyle changes and those managed with lifestyle changes alone. Participants will undergo MRI body composition at baseline and after 9 months. Conditions: Childhood Obesity Lead…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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Guideline
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Initiate semaglutide only in specialist obesity services or via shared care with clear primary-secondary care protocols for adults with BMI ≥30 kg/m²…
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Guideline
Obesity: Identification, Assessment and Management (NICE CG189)
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Use BMI thresholds to identify obesity (≥30 kg/m² in adults; ≥27.5 kg/m² in Asian populations) and offer structured first-line weight loss interventions…
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Clinical Brief
Weight-loss jabs will be offered on NHS for people at risk of further heart attacks
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Clinical Brief
Why weight-loss jabs work better for some people than others
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Genetic variations in appetite and digestion genes predict differential weight-loss responses to GLP-1 receptor agonists (Wegovy, Mounjaro), suggesting personalised medicine approaches may…
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New drug to stop ‘Ozempic butt’ muscle loss side effect of obesity jabs
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