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Clinical Trial ● Currently Recruiting NCT06974162

Metagenomics for Ocular Inflammation

Metagenomics for Ocular Inflammation — Recruiting • Rheumatology • NCT06974162.

📅 21 Jul 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
NCT ID
NCT06974162
Sponsor
Moorfields Eye Hospital NHS Foundation Trust
Start
2025-06-12
ClinicaliQ Trial Snapshot
  • Metagenomics for Ocular Inflammation — Recruiting • Rheumatology • NCT06974162.
  • What is being tested: Metagenomic sequencing is being evaluated as a diagnostic tool to identify infectious agents in patients with ocular inflammation when standard diagnostic tests have failed to identify a causative organism.
  • Patient eligibility overview: The study includes patients presenting with ocular inflammation of unknown or suspected infectious origin where conventional testing methods have not yielded a diagnosis.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The aim of this study is to apply a diagnostic test called 'metagenomic sequencing' to identify the involvement of potential infections in patients with ocular inflammation, where this hasn't been detected by currently available standard testing. For many people with ocular inflammation, no cause is ever found for their disease. In some cases, an infection or infectious trigger is suspected, but currently available tests are inadequate. Metagenomic sequencing can identify almost every globally known infection (bacteria, virus, fungi, parasites) in a sample. Therefore, it has the potential to identify an…

Eligibility Snapshot
  • : 1. 18 years of age or older with the capacity to consent 2. Standard of care has not determined a clinical diagnosis 3. Active ocular inflammation with risk of visual loss 4. Clinically suspected infectious or para-infectious cause of ocular inflammation

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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