Clinical Trials Archive - Page 2 of 16

recruiting PHASE4 Oncology NCT07073950

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

The purpose of the study is to evaluate the effect of BGF MDI compared with placebo MDI on cardiac and lung function when administered in participants diagnosed with COPD and…

Sponsor: AstraZeneca

View Trial ClinicalTrials.gov ↗

recruiting NA Respiratory / COPD / Asthma NCT06035120

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo instillation of AeriSeal…

Sponsor: Pulmonx Corporation

View Trial ClinicalTrials.gov ↗

recruiting PHASE2 Respiratory / COPD / Asthma NCT06496620

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

A Randomized, Double-blind, Placebo-controlled, Multiple Dose-Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Participants with Chronic Obstructive Pulmonary Disease (COPD).

Sponsor: Uniquity One (UNI)

View Trial ClinicalTrials.gov ↗

recruiting PHASE2 Respiratory / COPD / Asthma NCT07082738

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

This Phase IIb dose-ranging study will evaluate the efficacy and safety of 3 different doses of AZD6793 compared with placebo tablets in participants with moderate to very severe chronic obstructive…

Sponsor: AstraZeneca

View Trial ClinicalTrials.gov ↗

recruiting PHASE3 Cardiology / Cardiovascular NCT04045665

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients…

Sponsor: Icahn School of Medicine at Mount Sinai

View Trial ClinicalTrials.gov ↗

recruiting Cardiology / Cardiovascular NCT06393920

PulseSelect™ PFA Global Registry

The PulseSelect™ PFA Global Registry is a prospective, global, multi-center, observational post-approval study. Subjects will be treated with the PulseSelect™ PFA System and followed according to SOC.

Sponsor: Medtronic Cardiac Ablation Solutions

View Trial ClinicalTrials.gov ↗

recruiting NA Cardiology / Cardiovascular NCT04664686

Rate or Rhythm Control in CRT: the RHYTHMIC Study

70 patients with heart failure, AF and CRT with BiV

Sponsor: Guy's and St Thomas' NHS Foundation Trust

View Trial ClinicalTrials.gov ↗

recruiting PHASE2 Cardiology / Cardiovascular NCT07217067

A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

A randomized, placebo-controlled, participant-and investigator-blinded study to evaluate the efficacy in reducing atrial fibrillation burden as well as the safety, tolerability and pharmacokinetics of PKN605 in participants with atrial fibrillation

Sponsor: Novartis Pharmaceuticals

View Trial ClinicalTrials.gov ↗

recruiting NA Cardiology / Cardiovascular NCT05963698

The Fourth Left Atrial Appendage Occlusion Study

LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite…

Sponsor: Hamilton Health Sciences Corporation

View Trial ClinicalTrials.gov ↗

recruiting NA Cardiology / Cardiovascular NCT05976685

Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy

Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and cardioembolic stroke due to AF is its major complication. Direct oral anticoagulants (DOAC) reduce the risk of cardioembolism…

Sponsor: Insel Gruppe AG, University Hospital Bern

View Trial ClinicalTrials.gov ↗

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