Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase IV Cardiology / Cardiovascular
Pulmonary Hypertension: Intensification and Personalisation of Combination Rx
What is being tested: The trial evaluates whether implantable/remote monitoring technology can enable early assessment of drug efficacy and guide treatment intensification decisions in…
05 Jun 2026 NCT05825417
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
What is being tested: Two bispecific antibody-based regimens (Tec-DR and Tal-DR) are being compared against standard daratumumab-lenalidomide-dexamethasone (DRd) therapy in newly diagnosed multiple myeloma…
05 Jun 2026 NCT05552222
● Recruiting Cardiology / Cardiovascular
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma
What is being tested: Real-world effectiveness, safety, and patient-reported outcomes of standard-of-care antimyeloma treatments in relapsed/refractory multiple myeloma patients over 24 months, reflecting actual…
05 Jun 2026 NCT05160584
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) is being evaluated for long-term safety and efficacy when combined with standard heart failure…
05 Jun 2026 NCT07192952
● Recruiting Phase I Cardiology / Cardiovascular
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
What is being tested: JNJ-79635322, a novel investigational agent, is undergoing dose escalation and safety characterization in patients with relapsed or refractory multiple myeloma…
05 Jun 2026 NCT05652335
● Recruiting Cardiology / Cardiovascular
An Observational Post-marketing Study Using Commercially Approved Biosense Webster (BWI) Medical Devices for the Treatment of Participants With Cardiac Arrhythmias
What is being tested: Safety and performance of commercially approved Biosense Webster medical devices during routine cardiac arrhythmia mapping and ablation procedures in real-world…
05 Jun 2026 NCT04750798
● Recruiting Phase III Oncology
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
What is being tested: Amivantamab (a bispecific antibody targeting EGFR and MET) combined with pembrolizumab and carboplatin, compared to standard chemotherapy-immunotherapy combinations (pembrolizumab with…
05 Jun 2026 NCT07276399
● Recruiting Phase I Oncology
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
Drug Being Tested: JNJ-88549968, a novel therapeutic agent targeting CALR-mutated myeloproliferative neoplasms (MPNs), with the study establishing safety profile, recommended phase 2 dose, and…
05 Jun 2026 NCT06150157
active not recruiting Phase III
Atrasentan in Patients With IgA Nephropathy
Atrasentan reduced kidney disease progression in IgA nephropathy patients compared to placebo.
04 Jun 2026 NCT04573478
● Recruiting
The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
Study comparing whether people with RBD have more history of head injuries or contact sports than those without RBD.
04 Jun 2026 NCT06270290
active not recruiting Phase I / Phase II Diabetes / Metabolic
A Safety, Tolerability, and Efficacy Study of VX-264 in Participants With Type 1 Diabetes
VX-264 trial tested a new drug's safety and effectiveness in type 1 diabetes patients.
04 Jun 2026 NCT05791201
● Recruiting Phase II
A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)
GTX-102 injection being tested for safety and effectiveness in treating Angelman syndrome caused by different genetic mutations.
04 Jun 2026 NCT07157254
active not recruiting Phase IV Cardiology / Cardiovascular
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
Study comparing blood thinners alone versus blood thinners with ultrasound-assisted clot-dissolving device for moderate-to-high risk blood clots in the lungs.
04 Jun 2026 NCT04790370
● Recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis
Oral nizubaglustat tested against placebo for safety and effectiveness in children with rare inherited brain storage diseases.
04 Jun 2026 NCT07054515
● Recruiting Respiratory / COPD / Asthma
Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
What is being tested: This study investigates the inflammatory and physiological profiles in healthy lungs versus diseased lungs (specifically asthma and COPD), aiming to…
04 Jun 2026 NCT06144476
● Recruiting Phase II Oncology
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
What is being tested: Inavolisib (a PI3K inhibitor) combined with enzalutamide versus standard physician-selected alternatives (other androgen receptor pathway inhibitors or docetaxel) in biomarker-selected…
04 Jun 2026 NCT07287150
● Recruiting Phase IV Oncology
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
What is being tested: Long-term safety profile of lutetium (177Lu) vipivotide tetraxetan (AAA617), a radioligand therapy targeting PSMA-positive prostate cancer, through post-marketing surveillance to…
04 Jun 2026 NCT05803941
● Recruiting Oncology
Trans and Non-binary Prostate-Specific Antigen Reference Interval Determination Study
Testing focus: This study establishes PSA reference intervals (normal ranges) specifically for trans women and non-binary individuals with prostates, addressing a current evidence gap…
04 Jun 2026 NCT06987045
● Recruiting Oncology
Understanding the Feasibility of a Co-designed Pre-radiotherapy Exercise Programme – A Single-arm Study
What is being tested: A feasibility study evaluating a co-designed, pre-radiotherapy exercise programme consisting of 20-minute exercise sessions for patients with stage I-III non-small…
04 Jun 2026 NCT07554677
● Recruiting Gastroenterology
Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation
What is being tested: INTERLIVER evaluates whether microarray analysis of liver transplant biopsies can identify molecular patterns that correlate with histological findings and predict…
04 Jun 2026 NCT03193151
● Recruiting Cardiology / Cardiovascular
The “Global Paradise System” Registry
What is being tested: The GPS Registry is observing real-world outcomes in patients receiving standard clinical care, with additional collection of home blood pressure…
04 Jun 2026 NCT05027685
● Recruiting Phase II Respiratory / COPD / Asthma
Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
What is being tested: The trial compares volatile anaesthetic sedation against conventional intravenous sedation approaches in mechanically ventilated ICU patients to evaluate effects on…
04 Jun 2026 NCT06014138
● Recruiting Respiratory / COPD / Asthma
Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion
What is being tested: The study investigates how removing fluid from around the lungs (thoracocentesis) affects neural respiratory drive—the brain's signal to breathe—in patients…
04 Jun 2026 NCT05945043
● Recruiting Respiratory / COPD / Asthma
Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
What is being tested: The study evaluates health-related quality of life (HRQoL) outcomes in patients with chronic respiratory failure and measures how clinical interventions…
04 Jun 2026 NCT04236726
● Recruiting Cardiology / Cardiovascular
European Aortic Data Collection Project
What is being tested: Safety and real-world performance of Cook's Custom-Made Stent-graft Devices (CMD) for endovascular aortic treatment across diverse aortic pathologies through prospective…
04 Jun 2026 NCT05896397
● Recruiting Phase I Oncology
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
Drug Being Tested: Farletuzumab ecteribulin (MORAb-202), a folate receptor alpha (FRα)-targeting antibody-drug conjugate designed to deliver chemotherapy directly to cancer cells expressing this receptor.…
04 Jun 2026 NCT04300556
● Recruiting Phase I Oncology
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
What is being tested: LY4584180, a novel investigational agent, is being evaluated for its safety, efficacy, pharmacokinetics, and pharmacodynamics in adults with relapsed or…
04 Jun 2026 NCT07226843
active not recruiting Neurology
Electrical Impedance Tomography of Epilepsy
One-sentence summary: Study testing if EIT brain imaging produces accurate, reproducible results in epilepsy patients compared to MRI, CT, and EEG.
03 Jun 2026 NCT03050931
● Recruiting Phase III Neurology
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
XEN1101 added to existing treatment reduced seizures in patients with primary generalized tonic-clonic seizures compared to placebo.
03 Jun 2026 NCT05667142
active not recruiting Phase III Oncology
A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma
Subcutaneous injection of two cancer drugs works as well as intravenous infusion for untreated advanced melanoma.
03 Jun 2026 NCT05625399
● Recruiting Phase III
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ – ColdU and SD)
Barzolvolimab reduces symptoms of cold-induced urticaria and dermographism better than placebo in patients uncontrolled on antihistamines.
03 Jun 2026 NCT07266402
active not recruiting Phase III Rheumatology
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Monthly ianalumab injections added to standard lupus treatment reduced disease activity better than placebo.
03 Jun 2026 NCT05624749
● Recruiting Phase III Diabetes / Metabolic
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
Orforglipron, a daily weight-loss pill, is being tested in teenagers with obesity or overweight with health complications over 18 months.
03 Jun 2026 NCT06672939
● Recruiting Phase I Oncology
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
What is being tested: Tulmimetostat (a novel STAT3 inhibitor) combined with either darolutamide or abiraterone, compared to darolutamide monotherapy, to assess safety, tolerability, and…
03 Jun 2026 NCT07190300
● Recruiting Phase II Rheumatology
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH – SLE/LN)
What is being tested: Rapcabtagene autoleucel, a one-time CAR-T cell therapy administered after lymphodepletion, in patients with active, treatment-refractory systemic lupus erythematosus or lupus…
03 Jun 2026 NCT06581198
● Recruiting Phase II
A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy
What is being tested: Sparsentan, a dual endothelin and angiotensin II receptor antagonist, is being evaluated for its nephroprotective efficacy and safety in patients…
03 Jun 2026 NCT04663204
● Recruiting Phase II Cardiology / Cardiovascular
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis
What is being tested: LTI-03, an inhaled experimental medication designed to treat Idiopathic Pulmonary Fibrosis (IPF) by addressing the underlying pathophysiology of progressive lung…
03 Jun 2026 NCT06968845
● Recruiting Cardiology / Cardiovascular
A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)
Treatment being tested: Garadacimab effectiveness and safety in real-world clinical practice for hereditary angioedema (HAE) management, with long-term follow-up data collected over 48 months…
03 Jun 2026 NCT07001280
● Recruiting Cardiology / Cardiovascular
Developing a Brief Intervention to Communicate Cardiovascular Risk to Patients Presenting to the Emergency Department With Chest Pain: a Co-Production Approach. Phase 2.
What is being tested: A brief intervention designed to communicate future cardiovascular risk to emergency department patients with chest pain who have not had…
03 Jun 2026 NCT06903442
● Recruiting Phase III Cardiology / Cardiovascular
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
What is being tested: Two novel bispecific antibody combinations (talquetamab plus pomalidomide, and talquetamab plus teclistamab) are being compared against standard treatment regimens (EPd…
03 Jun 2026 NCT06208150
● Recruiting Phase I Oncology
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
What is being tested: AZD5335, an antibody-drug conjugate, is being evaluated both as a standalone treatment and combined with established anti-cancer agents to assess…
03 Jun 2026 NCT05797168
● Recruiting Phase III Oncology
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator’s Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
What is being tested: Glofitamab monotherapy (a CD20/CD3 bispecific antibody) is being compared against standard salvage regimens (rituximab-bendamustine or rituximab-lenalidomide) in patients with relapsed…
03 Jun 2026 NCT06084936
● Recruiting Oncology
Vaginal Fluid Derived Biomarkers in the Early Detection and Evolution of Gynaecological Cancers
What is being tested: Vaginal fluid biomarkers are being investigated as potential early detection tools for gynaecological cancers by comparing specific molecular markers in…
03 Jun 2026 NCT07622953
active not recruiting Phase III Gastroenterology
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
A drug called resmetirom tested to see if it prevents liver disease progression in patients with advanced fatty liver cirrhosis.
02 Jun 2026 NCT05500222
active not recruiting Cardiology / Cardiovascular
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
Comatose cardiac arrest survivors randomly assigned to different sedation depths, body temperatures, and blood pressure targets to find optimal treatment combinations.
02 Jun 2026 NCT05564754
● Recruiting Gastroenterology
The Effects of Postbiotic Supplementation in Female Athletes
Postbiotic supplement versus placebo in active women to assess whether it reduces gut and stomach symptoms during menstrual cycles and exercise.
02 Jun 2026 NCT07580118
active not recruiting Phase I / Phase II Dermatology
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
Trial testing epcoritamab alone or combined with other drugs for B-cell non-Hodgkin lymphoma across ten treatment arms.
02 Jun 2026 NCT04663347
● Recruiting Phase III
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich’s Ataxia
Study testing omaveloxolone safety and effectiveness in children aged 2-15 with Friedreich's ataxia over three years.
02 Jun 2026 NCT06953583
active not recruiting Phase III Oncology
A Study of DB-1303/BNT323 vs Investigator’s Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)
DB-1303/BNT323 versus standard chemotherapy for HER2-low, hormone receptor positive advanced breast cancer, measuring time to disease progression.
02 Jun 2026 NCT06018337
● Recruiting Phase II Oncology
Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
What is being tested: Trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate, is being compared against standard CDK4/6 inhibitor-based endocrine therapy as first-line treatment for HR-positive/HER2-low…
02 Jun 2026 NCT06486883