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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Diabetes / Metabolic
Low EnerGy DiEt iN Adolescents With Obesity and Type 2 Diabetes: The LEGEND Study
Testing: A feasibility study investigating recruitment/retention rates for low energy diet (LED) interventions in adolescents with type 2 diabetes and obesity, with measurement of…
09 Jul 2026 NCT06572345
● Recruiting Cardiology / Cardiovascular
Abbott Structural Heart Device Registry
What is being tested: Safety and performance of Abbott's structural heart devices in real-world clinical practice, using data collected from routine hospital procedures rather…
09 Jul 2026 NCT06590467
● Recruiting Phase III Oncology
Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)
What is being tested: Surovatamig (a subcutaneous monoclonal antibody) administered as consolidation therapy following initial treatment in patients with CLL/SLL, focusing on therapeutic efficacy…
09 Jul 2026 NCT07509151
● Recruiting Phase I / Phase II
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Gene therapy trial testing whether a single injection can enable the body to produce its own clotting factor in severe haemophilia B patients.
08 Jul 2026 NCT06379789
active not recruiting Phase I Neurology
A Study to Assess THN391 in Subjects With Alzheimer’s Disease
Early-stage trial testing whether THN391 drug is safe and tolerable in Alzheimer's disease patients compared to placebo.
08 Jul 2026 NCT06814730
active not recruiting Phase III Oncology
177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer
Radioactive lutetium treatment improved survival compared to hormone therapy in men with advanced prostate cancer resistant to standard hormonal treatment.
08 Jul 2026 NCT04689828
active not recruiting Phase III
Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)
Depemokimab was compared to mepolizumab for treating difficult-to-control EGPA in adults already on standard treatment.
08 Jul 2026 NCT05263934
active not recruiting
LIQUIBAND FIX8® for Ventral Incisional Hernia
Real-world safety and performance data on LiquiBand FIX8, a CE-marked adhesive device for securing mesh in ventral incisional hernia repair.
08 Jul 2026 NCT07295379
active not recruiting Phase III
A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis
Trial testing two new drugs alone and combined for generalised myasthenia gravis, measuring safety, effectiveness, and how the body responds.
08 Jul 2026 NCT05070858
active not recruiting Phase III Oncology
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
Trial testing if adding epcoritamab injections to standard rituximab and lenalidomide improves outcomes in adults with relapsed/refractory follicular lymphoma.
08 Jul 2026 NCT05409066
active not recruiting
Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea
Study examines whether CPAP therapy reduces physiological signal complexity in obstructive sleep apnoea patients over six months.
08 Jul 2026 NCT07406620
active not recruiting Phase I / Phase II
Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma
Testing whether combining vorasidenib with standard chemotherapy is safe and effective for IDH-mutant brain tumours.
08 Jul 2026 NCT06478212
active not recruiting Phase II Infectious Disease
Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)
Bepirovirsen compared to placebo for treating people with both HIV and hepatitis B infection, measuring effectiveness and safety.
08 Jul 2026 NCT06497504
● Recruiting Oncology
Robotic Prostatectomy Artificial Intelligence Low Pressure Pain (RALP) Trial
What is being tested: Feasibility of using artificial intelligence to review operative outcomes, specifically pain levels, when comparing two commonly used robotic surgical devices…
08 Jul 2026 NCT06915909
● Recruiting Phase IV Rheumatology
Stopping PPI Therapy in Inactive IBD
What is being tested: The feasibility and safety of withdrawing proton pump inhibitor (PPI) therapy in patients with inactive inflammatory bowel disease (IBD), with…
08 Jul 2026 NCT07691138
● Recruiting Rheumatology
NAZA – Nottingham/Astra ZenecA Prospective IBD Cohort Study
What is being tested: This observational cohort study compares inflammatory markers between patients with inflammatory bowel disease (IBD) and non-IBD controls to identify potential…
08 Jul 2026 NCT06956703
● Recruiting Cardiology / Cardiovascular
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
What is being tested: The trial compares two coronary imaging strategies—a calcium modification approach guided by coronary CT angiography (CCTA) versus standard imaging protocols—to…
08 Jul 2026 NCT07286578
● Recruiting Phase II Oncology
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
What is being tested: Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy, a genetically modified T-cell immunotherapy designed to target and eliminate CD19-expressing B cells…
08 Jul 2026 NCT06193889
● Recruiting Phase III Oncology
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma
What is being tested: Odronextamab (an experimental bispecific antibody) combined with chemotherapy versus the standard rituximab-chemotherapy regimen in treatment-naïve adult patients with diffuse large…
08 Jul 2026 NCT06091865
● Recruiting Phase I Oncology
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
What is being tested: Ponatinib, a tyrosine kinase inhibitor, is being evaluated for safety, tolerability, pharmacokinetics, and efficacy in paediatric patients aged 1-18 years…
08 Jul 2026 NCT03934372
● Recruiting Phase III
A Study of Brenipatide in Participants With Alcohol Use Disorder
Brenipatide tested against placebo over 56 weeks to assess whether it safely reduces alcohol use in people with alcohol use disorder.
07 Jul 2026 NCT07219953
active not recruiting Phase III Oncology
Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer
Durvalumab added to standard BCG therapy improved outcomes compared to BCG alone in non-muscle-invasive bladder cancer.
07 Jul 2026 NCT03528694
active not recruiting Phase III
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors
Emicizumab injections prevent bleeding in babies under 12 months with severe haemophilia A, with safety and effectiveness monitored over 8 years.
07 Jul 2026 NCT04431726
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
A trial testing whether eloralintide injection reduces knee osteoarthritis pain in overweight or obese adults over 75 weeks.
07 Jul 2026 NCT07353931
active not recruiting Oncology
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Real-world study observing outcomes in advanced prostate cancer patients treated with darolutamide plus hormone therapy, with or without chemotherapy.
07 Jul 2026 NCT07344779
● Recruiting
The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score
What is being tested: The REED Score is a clinical tool designed to identify adults over 65 who have experienced a long lie (remaining…
07 Jul 2026 NCT07158554
● Recruiting Cardiology / Cardiovascular
Sixth Generation High-sensitivity Cardiac Troponin T for the Early Rule Out of Myocardial Infarction: a Controlled Before and After Study
What is being tested: A sixth-generation high-sensitivity cardiac troponin T assay evaluated in a controlled before-and-after study design to determine its ability to safely…
07 Jul 2026 NCT07636642
● Recruiting Oncology
RESCUE: A Workplace Dietary Intervention for UK Firefighters
What is being tested: A workplace dietary intervention programme designed to improve nutritional habits and food choices among UK firefighters, addressing the specific challenges…
07 Jul 2026 NCT07687849
active not recruiting Phase I / Phase II
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
New dual-targeted CAR-T cell therapy tested in relapsed/refractory B-cell lymphoma and high-risk newly diagnosed DLBCL.
06 Jul 2026 NCT05421663
active not recruiting Phase I Oncology
Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer
Trial testing new cancer drug amivantamab alone and combined with existing treatments in advanced lung cancer patients to find safe, effective doses.
06 Jul 2026 NCT02609776
● Recruiting Phase III Gastroenterology
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn’s Disease
This trial tests a new drug called Afimkibart to treat moderate-to-severe Crohn's disease, comparing it against placebo.
06 Jul 2026 NCT06819891
active not recruiting Phase I Oncology
A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer
This study tested whether a new prostate cancer drug (ARN-509) can be safely combined with abiraterone acetate, and whether dose adjustments are needed.
06 Jul 2026 NCT02123758
active not recruiting Phase I Oncology
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Trial testing whether teclistamab combined with other cancer drugs is safe and effective for multiple myeloma patients.
06 Jul 2026 NCT04722146
active not recruiting Phase I / Phase II Oncology
An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin’s Lymphoma
Testing two new drug combinations with glofitamab in patients with relapsed/refractory B-cell lymphoma to find safe doses and assess effectiveness.
06 Jul 2026 NCT03533283
● Recruiting Phase II / Phase III
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
A trial testing whether a new drug (atumelnant) safely and effectively treats congenital adrenal hyperplasia in children.
06 Jul 2026 NCT07159841
● Recruiting
AI Timing in Chest X-ray Interpretation Using Eye-Tracking
Study tests whether showing AI analysis before or after clinicians initially review chest X-rays affects their interpretation decisions and AI trust.
06 Jul 2026 NCT07675694
● Recruiting Phase III
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism
Baxdrostat reduced blood pressure and normalised hormone levels better than placebo in primary aldosteronism patients.
06 Jul 2026 NCT07007793
active not recruiting Phase III Oncology
An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
Apalutamide combined with hormone therapy improved metastasis-free survival in high-risk prostate cancer patients receiving radiotherapy.
06 Jul 2026 NCT02531516
● Recruiting Phase III Rheumatology
A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)
Trial testing whether baricitinib is safe and effective for treating systemic juvenile idiopathic arthritis in children aged 1-18 years.
06 Jul 2026 NCT04088396
● Recruiting Phase II
Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)
Infliximab did not improve outcomes in acute pancreatitis compared to placebo in this randomised controlled trial.
06 Jul 2026 NCT03684278
active not recruiting
Global Patient Registry of Inherited Retinal Diseases
This registry collects data on inherited retinal disease patients worldwide to understand disease progression and improve how doctors manage these conditions.
06 Jul 2026 NCT05957276
● Recruiting Respiratory / COPD / Asthma
A Trial Evaluating Novel Technologies for the Diagnosis of Asthma The LUNG-TECH Trial
Novel diagnostic technologies are being evaluated across three pathways to determine their clinical utility in asthma diagnosis, including their ability to differentiate asthma from…
06 Jul 2026 NCT05819944
● Recruiting Mental Health / Psychiatry
INCLUDE-CKD: INCLUsive Digital carE for Chronic Kidney Disease
What is being tested: MyRenalCare, a digital health app designed to support management and self-care in chronic kidney disease (CKD) patients, with evaluation of…
06 Jul 2026 NCT07613593
● Recruiting Cardiology / Cardiovascular
Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation – APOLLO-EU Trial
Intervention being tested: Safety and efficacy of Medtronic Intrepid™ Transcatheter Mitral Valve Replacement (TMVR) system as a transfemoral approach in patients with significant mitral…
06 Jul 2026 NCT05496998
● Recruiting Phase III Cardiology / Cardiovascular
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
What is being tested: JNJ-79635322 is being directly compared with a BCMA×CD3 bispecific antibody—both novel immunotherapies designed to engage T cells against BCMA-expressing myeloma…
06 Jul 2026 NCT07258511
● Recruiting
Hyaluronic Acid and Polynucleotides for Supra-bony Defects
A pilot study comparing gum surgery alone versus surgery combined with a special gel to treat deep gum defects.
02 Jul 2026 NCT06309719
active not recruiting Phase I / Phase II Gastroenterology
Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients
QEL-001 Trial Summary A study testing a personalised cell therapy to help liver transplant patients accept their donor organ without long-term immunosuppression.
02 Jul 2026 NCT05234190
active not recruiting Phase II Oncology
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.
JDQ443 alone as initial treatment for advanced lung cancer with KRAS G12C mutation and low immune marker or specific genetic features.
02 Jul 2026 NCT05445843
active not recruiting Phase III
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
Trial comparing iberdomide versus lenalidomide as maintenance therapy after stem cell transplant in newly diagnosed myeloma patients.
02 Jul 2026 NCT05827016
active not recruiting Phase III Infectious Disease
A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
Two-drug HIV treatment works as well as three-drug treatment, with simpler dosing and fewer side effects in treatment-naive adults.
02 Jul 2026 NCT05979311