Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
Treatment being tested: Trastuzumab deruxtecan (T-DXd) combined with pembrolizumab compared to platinum-based chemotherapy with pembrolizumab as first-line therapy for HER2-overexpressing advanced non-squamous non-small cell…
02 Jul 2026 NCT06899126
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
What is being tested: GSK3862995B, a novel investigational drug, is being evaluated for its effectiveness and safety in treating bronchiectasis, alongside assessment of pharmacokinetics…
02 Jul 2026 NCT07201051
● Recruiting Cardiology / Cardiovascular
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
What is being tested: The Rapidlink device is being evaluated for safety and effectiveness as an aid in open surgical repair of thoracic aortic…
02 Jul 2026 NCT07078383
● Recruiting Phase III Cardiology / Cardiovascular
Thromboprophylaxis in Lower Limb Immobilisation
What is being tested: The clinical and cost effectiveness of thromboprophylaxis (blood clot prevention) in patients immobilised with plaster casts or splints following injury,…
02 Jul 2026 NCT06370273
● Recruiting Phase II Oncology
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton’s Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
NX-5948, a novel protein degradation agent, is being tested as a potential treatment for patients with relapsed/refractory CLL/SLL who have exhausted standard therapeutic options…
02 Jul 2026 NCT07221500
● Recruiting Phase III
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
Trial testing whether atogepant tablets safely reduce migraine frequency in children and teenagers aged 6-17 years over 12 weeks.
01 Jul 2026 NCT05711394
active not recruiting Phase III
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
Gene-edited stem cell therapy significantly improves severe sickle cell disease in children who cannot tolerate standard treatment.
01 Jul 2026 NCT05329649
active not recruiting Neurology
Validation of a Novel Functional Food Designed to Meet the Nutritional Needs of People Living With Parkinson’s Disease
A 12-week study testing a specially designed drink with added fibre and vitamins to improve constipation and quality of life in Parkinson's disease patients.
01 Jul 2026 NCT06697626
active not recruiting Phase IV Oncology
Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM)
Regular blood tests measuring TNF inhibitor levels help maintain disease control better than standard care in rheumatoid arthritis patients.
01 Jul 2026 NCT06440629
active not recruiting Phase III
Open-Label Extension Study of BBP-418 (Ribitol) for LGMD2I/R9
Long-term safety and effectiveness study of oral ribitol for a rare inherited muscle weakness condition in previous trial participants.
01 Jul 2026 NCT07678775
active not recruiting Phase III Oncology
A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)
Adding abemaciclib to standard hormone therapy may delay cancer progression in men with advanced prostate cancer.
01 Jul 2026 NCT05288166
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer’s Disease
Drug Being Tested: DNL628 is a novel therapeutic agent undergoing Phase 1b evaluation for safety, tolerability, pharmacokinetics and pharmacodynamics in early Alzheimer's disease using…
01 Jul 2026 NCT07328451
● Recruiting Phase I Neurology
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
CC-97540, a novel oral immunomodulatory agent, is being evaluated for safety, tolerability, efficacy and pharmacokinetics across three distinct autoimmune neurological conditions: relapsing and progressive…
01 Jul 2026 NCT06220201
● Recruiting Phase II Oncology
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) – Master Screening Protocol
What is being tested: DETERMINE evaluates targeted cancer treatments in rare cancers or common cancers with rare genetic mutations identified through routine molecular testing,…
01 Jul 2026 NCT05722886
● Recruiting Gastroenterology
Adiposity and Iron Requirements in Pregnancy
What is being tested: A double-blind randomized controlled trial investigating whether body fat (adiposity) affects how pregnant women respond to different daily iron supplementation…
01 Jul 2026 NCT06425796
● Recruiting Phase III Rheumatology
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn’s Disease
What is being tested: Duvakitug, a novel therapeutic agent, is undergoing Phase 3 evaluation for induction of remission in moderately to severely active Crohn's…
01 Jul 2026 NCT07184931
● Recruiting Phase II Oncology
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Drug being tested: Ponsegromab (a novel therapeutic agent) combined with standard systemic chemotherapy, compared to chemotherapy alone with placebo, in treatment-naïve patients with metastatic…
01 Jul 2026 NCT06989437
● Recruiting Phase III Oncology
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
Treatment being tested: TDXd (trastuzumab deruxtecan) combined with chemotherapy and pembrolizumab versus standard chemotherapy plus trastuzumab and pembrolizumab as first-line therapy for metastatic HER2-positive…
01 Jul 2026 NCT06731478
● Recruiting Phase I Oncology
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Drug being tested: Sacituzumab tirumotecan (MK-2870), a targeted antibody-drug conjugate, is being evaluated as monotherapy or in combination with other treatments for advanced or…
01 Jul 2026 NCT06428409
● Recruiting Phase IV
Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa
This study tracks how well efanesoctocog alfa prevents joint bleeds in haemophilia A patients receiving routine preventive treatment over the long term.
30 Jun 2026 NCT06940830
● Recruiting Phase III
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Clemizole added to standard treatment reduced seizures more than placebo in Dravet syndrome patients.
30 Jun 2026 NCT04462770
active not recruiting Phase I Oncology
A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias
New drug SNDX-5613 combined with chemotherapy tested for safety and effectiveness in newly diagnosed acute myeloid leukaemia.
30 Jun 2026 NCT06226571
● Recruiting Phase III Women's Health
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
Long-term study evaluating Mim8, a new factor VIII replacement therapy, for preventing bleeds in haemophilia A patients with or without inhibitors.
30 Jun 2026 NCT05685238
● Recruiting Diabetes / Metabolic
A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine
Researchers are investigating how kidney injury develops after heart surgery using heart-lung machines by studying biomarkers in blood and urine samples.
30 Jun 2026 NCT06772025
active not recruiting Mental Health / Psychiatry
Exploring Equine-Assisted Psychotherapy as an Intervention for Those Who Have Received a Diagnosis of Emotionally Unstable Personality Disorder
Study testing whether working with horses improves emotional regulation and engagement in inpatients with emotionally unstable personality disorder.
30 Jun 2026 NCT07261033
● Recruiting Phase I / Phase II Rheumatology
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Early-stage trial testing genetically-modified immune cells to treat severe autoimmune diseases (systemic sclerosis and rheumatoid arthritis).
30 Jun 2026 NCT07473154
● Recruiting Phase II / Phase III
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Trial comparing new eye injection tiespectus against standard aflibercept treatment for wet age-related macular degeneration.
30 Jun 2026 NCT07440225
● Recruiting Phase I
PS-002 for the Treatment of IgA Nephropathy in Adults
PS-002 is a novel therapeutic agent being tested in a first-in-human trial to evaluate its safety, tolerability, and preliminary effectiveness in treating primary IgA…
30 Jun 2026 NCT07182227
● Recruiting Respiratory / COPD / Asthma
Novel Technologies for Respiratory Virus Identification
What is being tested: Novel diagnostic technologies designed to improve the speed and accuracy of identifying respiratory viruses, addressing limitations of current detection methods…
30 Jun 2026 NCT05661032
● Recruiting Respiratory / COPD / Asthma
Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF)
What is being tested: Nitrate-rich beetroot juice supplementation as a potential intervention to improve exercise capacity in IPF patients, building on evidence that interval-based…
30 Jun 2026 NCT06488638
● Recruiting Phase III Diabetes / Metabolic
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
What is being tested: VX-880 is an investigational infusion therapy being evaluated for safety, tolerability, and efficacy in treating Type 1 diabetes, specifically targeting…
30 Jun 2026 NCT04786262
● Recruiting Cardiology / Cardiovascular
Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
What is being tested: The study evaluates whether personalised monitoring of cerebral autoregulation during cardiac surgery—using NIRS and transcranial Doppler to identify individual MAP…
30 Jun 2026 NCT05595954
● Recruiting Oncology
Low-carbohydrate Diet and Low-Density Lipoprotein – Cholesterol (LDL-c) Interindividual Variability
What is being tested: The trial investigates how individual patients respond differently to low-carbohydrate (ketogenic) diets in terms of LDL-cholesterol changes, recognising that the…
30 Jun 2026 NCT07675603
● Recruiting Phase III Cardiology / Cardiovascular
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
What is being tested: NNC0487-0111, a novel investigational therapy, is being evaluated against placebo for safety and efficacy in patients with HFpEF or HFmrEF…
30 Jun 2026 NCT07567001
● Recruiting Phase III Oncology
Adjuvant Tebentafusp in High Risk Ocular Melanoma
Treatment being tested: Tebentafusp (a TCR-engineered T-cell therapy) as adjuvant therapy following primary treatment in patients with high-risk uveal melanoma, aiming to prevent recurrence…
30 Jun 2026 NCT06246149
● Recruiting Oncology
The Ailliance Post-Market Clinical Study
What is being tested: Post-market performance and safety data for Medtronic devices used in cranial and spinal surgical procedures, with patient follow-up extending to…
30 Jun 2026 NCT05856370
● Recruiting Phase I Oncology
Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer
What is being tested: Multiple anti-cancer agents are being evaluated for safety, tolerability, pharmacokinetics, and preliminary efficacy in a platform study design, allowing simultaneous…
30 Jun 2026 NCT07590934
active not recruiting Phase III Oncology
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer
Adding lurbinectedin to atezolizumab maintenance therapy versus atezolizumab alone for extensive-stage small-cell lung cancer after initial chemotherapy.
29 Jun 2026 NCT05091567
● Recruiting
Muscle Function Response to Resistance Band Training in Older Adults With Impaired Muscle Power
Resistance band exercises improved muscle strength and balance in older adults with weak muscles.
29 Jun 2026 NCT07672834
● Recruiting Phase II
An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal Hyperplasia
Long-term study testing whether atumelnant is safe and effective for treating congenital adrenal hyperplasia.
29 Jun 2026 NCT06712823
● Recruiting
A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves
Registry tracking pain relief outcomes in patients having frozen nerve treatment for post-surgical chest pain.
29 Jun 2026 NCT05110989
● Recruiting Phase II Neurology
A Study of AAV2-GDNF in Adults With Moderate Parkinson’s Disease (REGENERATE-PD)
What is being tested: AAV2-GDNF is a gene therapy delivered surgically to the putamen (a key brain region affected in Parkinson's Disease) to potentially…
29 Jun 2026 NCT06285643
● Recruiting Oncology
Clinical Utility of ctDNA in Detecting Resistance Mechanisms and Delivering Precision Medicine to Cancer Patients
What is being tested: The clinical utility of circulating tumour DNA (ctDNA) analysis from blood samples to detect cancer resistance mechanisms and guide precision…
29 Jun 2026 NCT07673861
● Recruiting Phase III Cardiology / Cardiovascular
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Treatment being tested: Sonlicromanol, a novel investigational medicine designed to reduce fatigue symptoms and improve physical function (including balance control) in patients with primary…
29 Jun 2026 NCT06451757
● Recruiting Phase I Oncology
Study of CryptiVax-1001 in Maintenance Setting for Advanced Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
What is being tested: CryptiVax-1001, an immunotherapeutic vaccine, is being evaluated as a maintenance treatment in patients with advanced high-grade serous ovarian, fallopian tube,…
29 Jun 2026 NCT07665515
● Recruiting Oncology
Endoscopic Submucosal Dissection for Early GI Neoplasia in the United Kingdom
What is being tested: Endoscopic submucosal dissection (ESD) effectiveness and safety as a treatment approach for early gastrointestinal neoplasia across multiple UK centres in…
29 Jun 2026 NCT03039309
active not recruiting Phase I / Phase II Oncology
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Trial testing pembrolizumab combined with various drugs to treat advanced prostate cancer resistant to hormone therapy.
26 Jun 2026 NCT02861573
active not recruiting Phase I
A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
Trial comparing two manufacturing methods of teclistamab to ensure the new process produces equivalent drug with same effectiveness in multiple myeloma.
26 Jun 2026 NCT06425991
active not recruiting Phase II Infectious Disease
SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.
Two new drugs tested together in hepatitis D patients to check if they're safe and effective.
26 Jun 2026 NCT05461170
active not recruiting Phase I Respiratory / COPD / Asthma
A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months
Two new mRNA vaccines against RSV and related respiratory viruses are being tested for safety and effectiveness in infants aged 5-24 months.
26 Jun 2026 NCT05743881