Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I
Study of BHV-1400 in IgA Nephropathy
What is being tested: BHV-1400, a novel investigational treatment, is being evaluated for safety and tolerability in patients with IgA Nephropathy (IgAN), the most…
02 Jun 2026 NCT07054684
● Recruiting Phase I Cardiology / Cardiovascular
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Being Tested: Surzetoclax, an oral agent, administered alone or combined with established subcutaneous/oral antimyeloma treatments, to evaluate safety profile and disease activity changes in…
02 Jun 2026 NCT06953960
● Recruiting Cardiology / Cardiovascular
Heart Failure Carer Support Programme: Implementation Testing in the UK.
What is being tested: An implementation programme designed to provide structured support and preparation for family carers of heart failure patients, addressing the gap…
02 Jun 2026 NCT07373041
● Recruiting Phase III Oncology
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician’s Choice in Subjects With Relapsed Small Cell Lung Cancer
What is being tested: Ifinatamab deruxtecan (I-DXd), a novel antibody-drug conjugate targeting DLL3, is being compared against standard physician-selected chemotherapy in patients with relapsed…
02 Jun 2026 NCT06203210
● Recruiting Phase III Oncology
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
What is being tested: A triple combination therapy consisting of subcutaneous epcoritamab (bispecific antibody), intravenous rituximab (monoclonal antibody), and oral lenalidomide (immunomodulatory agent) in…
02 Jun 2026 NCT06191744
● Recruiting Phase I Oncology
Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment
What is being tested: Pelabresib pharmacokinetics and safety in patients with advanced malignancies, specifically comparing drug exposure and clearance between those with hepatic impairment…
02 Jun 2026 NCT07422610
● Recruiting Phase II
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Tafasitamab was tested in adults with autoimmune blood disorders to assess whether it was safe and effective.
01 Jun 2026 NCT07104565
active not recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
Trial testing a new add-on treatment (taldefgrobep alfa) alongside existing spinal muscular atrophy medicines to see if it helps and is safe.
01 Jun 2026 NCT05337553
active not recruiting Diabetes / Metabolic
EasiVits Acceptability & Tolerance Study
EasiVits trial tested new low-carbohydrate, unflavoured vitamin supplements designed to improve adherence in children with metabolic disorders requiring restricted diets.
01 Jun 2026 NCT07619170
active not recruiting Phase III Oncology
A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.
Adding tazemetostat to lenalidomide and rituximab improves progression-free survival in relapsed/refractory follicular lymphoma compared to placebo.
01 Jun 2026 NCT04224493
active not recruiting Phase II
A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma
TrAVeRse Trial Summary Acalabrutinib, venetoclax and rituximab combination therapy for untreated mantle cell lymphoma, testing whether maintenance treatment improves outcomes.
01 Jun 2026 NCT05951959
● Recruiting Dermatology
Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib
Ritlecitinib (JAK3 inhibitor) shows effective hair regrowth in severe alopecia areata patients in routine clinical practice.
01 Jun 2026 NCT06531109
● Recruiting Phase III Oncology
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Treatment being tested: BNT327 (pumitamig), a novel investigational therapy, combined with standard chemotherapy (etoposide/carboplatin) versus the current standard of care atezolizumab plus chemotherapy in…
01 Jun 2026 NCT06712355
● Recruiting
Diagnostic and Therapeutic Applications in Microarrays in Organ Transplantation
What is being tested: Microarray-based molecular diagnostic approaches to replace or supplement the current Banff Classification consensus system for identifying kidney transplant dysfunction, using…
01 Jun 2026 NCT01299168
● Recruiting Rheumatology
A Prospective Randomised Study of Treatment Selection Based on Epigenetic Markers Versus Standard of Care Treatment Selection in Adults With CROHN’s Disease
What is being tested: Epigenome-guided treatment selection for biologic therapy in active Crohn's disease, comparing personalised epigenetic marker-based approaches against standard-of-care treatment protocols to…
01 Jun 2026 NCT07363044
● Recruiting Phase II Respiratory / COPD / Asthma
Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis
What is being tested: PIPE-791, a novel investigational agent, is being evaluated in a Phase 2 randomised controlled trial to assess its efficacy, safety,…
01 Jun 2026 NCT07284459
● Recruiting Oncology
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
What is being tested: A computer programme designed to assist emergency department clinicians in earlier recognition and diagnosis of three major conditions—cancer, COPD, and…
01 Jun 2026 NCT07391280
● Recruiting Phase I Oncology
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
What is being tested: Pembrolizumab (an anti-PD-1 immunotherapy checkpoint inhibitor) is being evaluated for efficacy and safety in pediatric patients with advanced solid tumors,…
01 Jun 2026 NCT02332668
● Recruiting Phase III Oncology
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
Treatment being tested: Remibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, is being evaluated as an add-on therapy to standard-of-care treatment in generalised myasthenia gravis…
01 Jun 2026 NCT06744920
● Recruiting Phase I / Phase II
A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)
Gene therapy injection for Stargardt disease shows safety and early effectiveness in patients with ABCA4 gene mutations.
29 May 2026 NCT07161544
● Recruiting
PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group
This study tracks safety and effectiveness of a tiny glaucoma drainage device in patients whose eye pressure remains too high despite maximum medication.
29 May 2026 NCT07235592
active not recruiting Phase III Dermatology
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)
Long-term safety and effectiveness study of dupilumab injection in children aged six months to eighteen years with atopic dermatitis.
29 May 2026 NCT02612454
active not recruiting Phase I / Phase II Oncology
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin’s Lymphoma
Early-stage trial testing new cancer drug englumafusp alfa combined with existing treatments in patients with relapsed/refractory lymphoma.
29 May 2026 NCT04077723
active not recruiting Phase III Neurology
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Remibrutinib and teriflunomide showed similar effectiveness and safety for treating relapsing multiple sclerosis.
29 May 2026 NCT05156281
active not recruiting Phase III Neurology
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Remibrutinib was tested against teriflunomide in relapsing MS patients to compare how well each drug works and its safety profile.
29 May 2026 NCT05147220
active not recruiting
Stryker PEEK Customized Implant: A Prospective Post Market Follow Up to Evaluate Safety, Performance and Effectiveness
Custom PEEK implants safely restore bone and soft tissue defects in the skull and face over two years.
29 May 2026 NCT05362370
● Recruiting Phase II Rheumatology
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Trial testing whether new drug BI 3000202 at different doses improves lupus symptoms in adults over one year.
29 May 2026 NCT07409181
● Recruiting Phase I Oncology
A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies
What is being tested: ZI-MA4-1, a novel therapeutic agent, is undergoing evaluation for safety, tolerability, and clinical efficacy in patients with advanced solid malignancies…
29 May 2026 NCT07613723
● Recruiting Phase I Neurology
A Study to Assess the Effects of ACI-24.060 in Alzheimer’s Disease and in Down Syndrome (ABATE Study)
What is being tested: ACI-24.060, an investigational therapeutic agent, is being evaluated for its safety, tolerability, immunogenicity, and pharmacodynamic effects in two distinct populations:…
29 May 2026 NCT05462106
● Recruiting Respiratory / COPD / Asthma
Better Tests- Improving Diagnostic Accuracy and Prognostication in Interstitial Lung Diseases
What is being tested: Non-invasive diagnostic assessments designed to improve diagnostic accuracy and prognostication in interstitial lung diseases (ILD), addressing current weaknesses in available…
29 May 2026 NCT07615504
● Recruiting Phase III Respiratory / COPD / Asthma
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
What is being tested: Daraxonrasib (RMC-6236), a novel RAS(ON) inhibitor, is being evaluated against docetaxel chemotherapy for safety and efficacy in patients with RAS-mutated…
29 May 2026 NCT06881784
● Recruiting Phase III Cardiology / Cardiovascular
Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days
What is being tested: Obicetrapib (OBI), a novel CETP inhibitor, is being directly compared to bempedoic acid (BPA) for reducing LDL-cholesterol in adults with…
29 May 2026 NCT07614958
● Recruiting Phase III Cardiology / Cardiovascular
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
What is being tested: L606 is being evaluated in a Phase 3 trial to assess its safety and efficacy in treating pulmonary hypertension secondary…
29 May 2026 NCT07285655
● Recruiting Phase II Oncology
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
What is being tested: This trial investigates ribociclib (CDK4/6 inhibitor) combined with either everolimus or temozolomide in pediatric and young adult patients with newly…
29 May 2026 NCT05843253
● Recruiting Oncology
Bearing nsPVA Embolization for Uterine Artery Embolization (BETTER-UAE)
What is being tested: Safety and performance of Bearing nsPVA (non-spherical polyvinyl alcohol) embolization particles as an embolic agent for uterine artery embolization in…
29 May 2026 NCT06153667
active not recruiting Phase III
Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP
A new drug (ALXN1850) was tested against placebo in children with bone disease to see if it improves bone health.
28 May 2026 NCT06079359
active not recruiting Phase IV Gastroenterology
Stopping Aminosalicylate Therapy in Inactive Crohn’s Disease
Stopping 5-ASA medication in inactive Crohn's disease works as well as continuing it.
28 May 2026 NCT03261206
● Recruiting Phase III
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
A new drug (empasiprubart) is being tested to see if it safely improves symptoms in adults with chronic nerve inflammation (CIDP).
28 May 2026 NCT07091630
active not recruiting Phase I / Phase II Oncology
A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
MTAPESTRY 101 Summary Trial testing anvumetostat drug alone and with chemotherapy in patients with MTAP-null cancers to find safe doses and effectiveness.
28 May 2026 NCT05094336
● Recruiting Phase III Diabetes / Metabolic
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
A new drug (Debio 4126) tested against placebo to control growth hormone levels in acromegaly patients previously treated with somatostatin analogs.
28 May 2026 NCT06930625
● Recruiting Phase III Oncology
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
What is being tested: AZD2265, a novel therapeutic agent, is being evaluated against standard-of-care treatments in patients with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC),…
28 May 2026 NCT07611110
● Recruiting Phase II Oncology
Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer
Treatment being tested: Camizestrant (an ER degrader) combined with atirmociclib (a CDK4/6 inhibitor) in women with ER-positive, HER2-negative advanced breast cancer who have previously…
28 May 2026 NCT07427394
● Recruiting Phase III Oncology
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
What is being tested: Camizestrant (AZD9833), a selective oestrogen receptor degrader (SERD), is being compared to standard adjuvant endocrine therapy (aromatase inhibitors or tamoxifen)…
28 May 2026 NCT05952557
● Recruiting Cardiology / Cardiovascular
A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition
What is being tested: This study evaluates liver health and function in boys with XLMTM (X-linked myotubular myopathy), a severe genetic muscle disorder caused…
28 May 2026 NCT06581146
● Recruiting Cardiology / Cardiovascular
The Effect of Time-Restricted Eating in Cardiometabolic Health
What is being tested: Time-restricted eating (TRE)—limiting daily food intake to a 6-12 hour window—is being investigated for its effects on cardiometabolic health markers,…
28 May 2026 NCT05866406
● Recruiting Phase I Cardiology / Cardiovascular
A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma
What is being tested: A phase 1b/2 dose-escalation and expansion study evaluating mezigdomide (cereblon E3 ligase modulator) combined with elranatamab (GPRC5D-targeted bispecific antibody) to…
28 May 2026 NCT06988488
● Recruiting Cardiology / Cardiovascular
Low-dose Interleukin-2 After Myocardial Infarction to Investigate Effects on Tissue-resident Regulatory T Cells
What is being tested: Low-dose interleukin-2 (ld-IL-2) administration in post-myocardial infarction patients to determine its effects on tissue-resident regulatory T cells (Tregs), assessed through…
28 May 2026 NCT07610538
● Recruiting Phase III Oncology
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
What is being tested: Long-term safety profile of luspatercept (ACE-536) in patients transitioning from completed or concluded parent clinical trials, using an open-label rollover…
28 May 2026 NCT04064060
● Recruiting Phase III Oncology
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
What is being tested: Zolbetuximab (a monoclonal antibody targeting claudin-18.2) combined with pembrolizumab (PD-1 inhibitor) and chemotherapy as a treatment for advanced gastric and…
28 May 2026 NCT06901531
active not recruiting Phase III Oncology
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
DESTINY-Gastric04 Summary Trastuzumab deruxtecan improves survival compared with ramucirumab plus paclitaxel in HER2-positive gastric cancer after trastuzumab treatment.
27 May 2026 NCT04704934