Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Oncology
Study of HLD-0915 in Patients With Metastatic Prostate Cancer
Drug and indication: HLD-0915 is being tested for safety and efficacy in metastatic prostate cancer patients who have failed previous systemic treatments, with planned…
26 Jun 2026 NCT06800313
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of How the Medicine Called “Etrasimod” Works in Children With the Gut Disease Called Ulcerative Colitis
Drug being tested: Etrasimod, a selective sphingosine-1-phosphate receptor modulator, is being evaluated for safety, efficacy, and pharmacokinetics in children aged 2 to <12 years…
26 Jun 2026 NCT07470879
● Recruiting Phase I Oncology
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
PC14586 (rezatapopt) is being evaluated as a monotherapy in patients with advanced solid tumors carrying the TP53 Y220C mutation, targeting restoration of mutant p53…
26 Jun 2026 NCT04585750
● Recruiting Phase II Respiratory / COPD / Asthma
Phase IIa Trial in Participants With Asthma to Evaluate Impact of Intranasal ETH47 on Development of Asthma-related Symptoms Following Rhinovirus Challenge
Treatment being tested: Intranasal ETH47, a novel therapeutic agent administered via nasal spray, designed to prevent asthma symptom development triggered by rhinovirus infection in…
26 Jun 2026 NCT07059767
● Recruiting Cardiology / Cardiovascular
Study of Lesion-Specific Invasive Haemodynamic Angina Thresholds
What is being tested: ORBITA-SOLAR investigates whether individual coronary stenoses have unique angina thresholds by measuring the specific degree of coronary flow reduction needed…
26 Jun 2026 NCT07386418
● Recruiting Phase III Cardiology / Cardiovascular
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency
What is being tested: Deucrictibant XR (extended-release) tablet for preventative treatment and deucrictibant IR (immediate-release) capsule for acute attack management in acquired angioedema due…
26 Jun 2026 NCT07266805
● Recruiting Oncology
Pancreatic Cancer Early Detection Consortium
What is being tested: The PRECEDE Consortium is investigating early detection and prevention strategies for pancreatic ductal adenocarcinoma (PDAC) in high-risk populations, including individuals…
26 Jun 2026 NCT04970056
● Recruiting Phase I Oncology
Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis
Treatment being tested: YTB323, a novel CAR-T cell therapy designed to target and eliminate autoreactive B cells in treatment-resistant generalized myasthenia gravis (gMG), representing…
26 Jun 2026 NCT06704269
active not recruiting Phase III Rheumatology
A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)
New drug JNJ-77242113 tested for treating psoriasis in difficult-to-treat areas like scalp, genitals, palms and soles.
25 Jun 2026 NCT06095102
active not recruiting Phase I / Phase II Oncology
Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor
Early-stage trial testing vimseltinib drug in patients with advanced cancers and tenosynovial giant cell tumours to find safe doses and effectiveness.
25 Jun 2026 NCT03069469
● Recruiting Phase III Dermatology
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis
Tralokinumab injections plus steroid cream safely and effectively treat moderate-to-severe eczema in young children and infants.
25 Jun 2026 NCT06311682
active not recruiting Cardiology / Cardiovascular
PLatform Study for INTracerebral Haemorrhage (PLINTH): Community-based Feasibility Study
PLINTH Study Summary This feasibility study tests whether a platform trial design is acceptable and workable for treating brain haemorrhage stroke survivors.
25 Jun 2026 NCT06078020
● Recruiting Phase III Diabetes / Metabolic
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Efruxifermin tested against placebo in 1,650 patients with liver scarring from fatty liver disease (stages 2-3, non-cirrhotic).
25 Jun 2026 NCT06215716
active not recruiting Phase I Oncology
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
New cancer drug GSK4381562 tested for first time in humans with advanced tumours to check safety and how the body processes it.
25 Jun 2026 NCT05277051
● Recruiting Phase I Neurology
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis
Being tested: Safety, tolerability, pharmacokinetics, immunogenicity, and pharmacodynamics of a new subcutaneous formulation of ocrelizumab (an anti-CD20 monoclonal antibody) in multiple sclerosis patients, with…
25 Jun 2026 NCT07667322
● Recruiting Phase II
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
What is being tested: AZD2373, a novel therapeutic agent, is undergoing dose-ranging evaluation for safety, tolerability, and efficacy specifically in APOL1-mediated kidney disease, targeting…
25 Jun 2026 NCT06824987
● Recruiting Phase II Respiratory / COPD / Asthma
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
Treatment being tested: AZD8965 at three different doses versus placebo in patients with idiopathic pulmonary fibrosis (IPF), assessed for efficacy, safety, and tolerability, with…
25 Jun 2026 NCT07652658
● Recruiting Phase II Respiratory / COPD / Asthma
Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma
What is being tested: Therapeutic equivalence of CHF5993 pMDI (a combination inhaler containing beclomethasone/formoterol/glycopyrronium) formulated with HFA-152a propellant versus the standard formulation, to confirm…
25 Jun 2026 NCT07301736
● Recruiting Phase III Oncology
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
What is being tested: The combination of TTFields (tumour-treating fields) delivered via NovoTTF-200T device alongside pembrolizumab immunotherapy and platinum-based chemotherapy in patients with metastatic…
25 Jun 2026 NCT06216301
● Recruiting Phase II Cardiology / Cardiovascular
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
What is being tested: A low-energy diet intervention to improve functional status and symptoms in patients with heart failure with preserved ejection fraction (HFpEF),…
25 Jun 2026 NCT05887271
● Recruiting Phase II Oncology
Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
Drug being tested: Surovatamig (AZD0486), a novel monotherapy agent, is being evaluated for efficacy, safety and tolerability in treating relapsed/refractory B-cell non-Hodgkin lymphoma in…
25 Jun 2026 NCT06526793
active not recruiting Phase II Gastroenterology
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
B-Sure Trial Summary This study tracks how long the benefits of bepirovirsen (an experimental hepatitis B treatment) last in patients after they stop taking…
24 Jun 2026 NCT04954859
active not recruiting Rare Diseases
A Prospective Study to Observe & Describe Clinical Outcomes of Alglucosidase Alfa Treatment in Patients ≤6 Months of Age With Infantile-onset Pompe Disease (IOPD)
Early alglucosidase alfa treatment in infantile-onset Pompe disease improves survival without breathing support and motor development at 52 weeks.
24 Jun 2026 NCT04848779
● Recruiting Phase III
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Trial testing a new drug (volrustomig) versus monitoring in head and neck cancer patients after chemoradiotherapy.
24 Jun 2026 NCT06129864
● Recruiting Gastroenterology
ENDO1000 – A UK-wide Endometriosis Research Project
ENDO1000 collects symptom data via app from 3000 UK people with endometriosis to identify diagnostic markers and personalised treatment approaches.
24 Jun 2026 NCT07240883
● Recruiting Phase III
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
This trial tests whether pridopidine slows ALS progression compared to placebo in adults over 96 weeks.
24 Jun 2026 NCT07322003
active not recruiting Phase III
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
Venglustat compared to standard treatment for reducing heart thickening in adults with Fabry disease over 18 months.
24 Jun 2026 NCT05280548
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive
What is being tested: The study compares the effectiveness and potency of salbutamol (albuterol) delivered via metered dose inhalers using two different propellant systems—HFA-152a…
24 Jun 2026 NCT06433921
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
What is being tested: A novel combination therapy pairing elranatamab (a bispecific antibody engaging T-cells and myeloma cells) with daratumumab and lenalidomide, compared against…
24 Jun 2026 NCT05623020
● Recruiting Phase I Oncology
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Drug being tested: CCS1477 (inobrodib), a novel therapeutic agent being evaluated for safety, tolerability, pharmacokinetics and biological activity in a Phase 1/2a trial across…
24 Jun 2026 NCT04068597
active not recruiting Phase III
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)
Mitapivat reduced anaemia in patients with non-transfusion-dependent thalassemia compared to placebo.
23 Jun 2026 NCT04770753
● Recruiting Phase II
A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
Phase 2 trial testing Claseprubart safety and effectiveness in adults with multifocal motor neuropathy.
23 Jun 2026 NCT06537999
active not recruiting Phase I / Phase II Oncology
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options
Entrectinib tested in children with advanced solid or brain tumours carrying specific gene fusions to find safe doses and effectiveness.
23 Jun 2026 NCT02650401
● Recruiting Phase III Mental Health / Psychiatry
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Trial testing whether adding NBI-1065845 to existing depression treatment works better than placebo for improving symptoms.
23 Jun 2026 NCT06963021
active not recruiting Phase II Oncology
A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Olaparib given before surgery and chemotherapy to shrink recurrent ovarian, peritoneal, or fallopian tube cancers.
23 Jun 2026 NCT02489006
● Recruiting Cardiology / Cardiovascular
Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades
What is being tested: Comparison of physiological pacing strategies versus traditional right ventricular (RV) pacing in patients undergoing first-time pacemaker implantation, specifically evaluating whether…
23 Jun 2026 NCT06052475
● Recruiting Oncology
Glasgow Low-dose CT and AI-based Diagnostics to Case Find Lung Cancer and Other Cardio-respiratory Long-term Conditions – Feasibility Study
What is being tested: Low-dose CT scanning combined with artificial intelligence diagnostics to detect lung cancer early and identify other cardio-respiratory long-term conditions in…
23 Jun 2026 NCT07372508
● Recruiting Phase III Oncology
A Study of ZL-1310 Versus Investigator’s Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
What is being tested: ZL-1310, a novel therapeutic agent, is being compared against standard investigator-selected treatments in patients with relapsed small cell lung cancer…
23 Jun 2026 NCT07218146
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Treatment being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist, is being evaluated at multiple doses versus placebo for weight management efficacy and safety…
23 Jun 2026 NCT07351045
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Intervention being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist at multiple doses, compared with placebo for weight management and glycaemic control in patients…
23 Jun 2026 NCT07351058
● Recruiting Cardiology / Cardiovascular
Nutritional Screening in Cardiovascular Disease
What is being tested: A comprehensive nutritional screening protocol combining questionnaires, blood/urine biomarkers, grip strength measurement, and body composition analysis in patients undergoing heart…
23 Jun 2026 NCT07409519
● Recruiting Phase I Oncology
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)
MK-1045 is being evaluated as a potential treatment for two distinct subtypes of non-Hodgkin lymphoma: follicular lymphoma (indolent/slow-growing) and diffuse large B-cell lymphoma (aggressive/fast-growing),…
23 Jun 2026 NCT07519772
active not recruiting Phase III Oncology
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
Ongoing access to avelumab treatment for patients benefiting from it in completed Pfizer trials, with safety monitoring.
22 Jun 2026 NCT05059522
active not recruiting Phase II / Phase III Rheumatology
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Litifilimab injections tested for efficacy and safety in adults with active cutaneous lupus unresponsive to antimalarial therapy.
22 Jun 2026 NCT05531565
active not recruiting Mental Health / Psychiatry
Designing and Evaluating a Classroom-Based Mental Health Programme for Adolescents.
A feasibility study testing whether a classroom mental health programme about psychosis and coping strategies works in Northern Ireland secondary schools.
22 Jun 2026 NCT07660874
active not recruiting Phase II
Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma
Acalabrutinib plus rituximab showed promise as a gentler first-line treatment option for elderly or frail patients with mantle cell lymphoma.
22 Jun 2026 NCT05004064
● Recruiting Phase III Neurology
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
This trial tests whether inhaled alprazolam stops prolonged seizures faster than placebo in people aged 12+.
22 Jun 2026 NCT05077904
● Recruiting Phase I / Phase II Rare Diseases
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Single intravenous gene therapy infusion (SGT-003) tested for safety and effectiveness in children with Duchenne muscular dystrophy across age groups.
22 Jun 2026 NCT06138639
● Recruiting Phase I Oncology
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
What is being tested: EP0062, a novel therapeutic agent, is being evaluated as a single agent and in combination with standard-of-care treatments to determine…
22 Jun 2026 NCT05573126
● Recruiting Gastroenterology
Natural History of Wilson Disease
What is being tested: A registry collecting clinical data and biological specimens from Wilson disease patients to establish optimal diagnostic testing methods and disease…
22 Jun 2026 NCT03334292