Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Oncology
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Treatment being tested: Tulmimetostat (DZR123/CPI-0209), a novel investigational agent evaluated as monotherapy and combined with enzalutamide, in a first-in-human trial assessing safety, tolerability, pharmacokinetics,…
22 Jun 2026 NCT04104776
● Recruiting Phase I Cardiology / Cardiovascular
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Treatment being tested: Linvoseltamab, an experimental monoclonal antibody targeting serum amyloid A, is being evaluated for safety and efficacy in adults with relapsed or…
22 Jun 2026 NCT06292780
● Recruiting Phase I Oncology
A Study to Assess the Safety and Anti-Tumor Activity of REGN7945 in Combination With Linvoseltamab in Adult Participants With Relapsed/Refractory Multiple Myeloma
What is being tested: REGN7945 combined with linvoseltamab (REGN5458), two experimental bispecific antibodies, in adults with relapsed/refractory multiple myeloma; this is the first-in-human study…
22 Jun 2026 NCT06669247
● Recruiting Cardiology / Cardiovascular
FeetSee Thermal Images Collection Protocol in Diabetes Patients
What is being tested: FeetSee thermal imaging technology is being evaluated as a potential early detection tool for diabetic foot ulcers by collecting thermal…
22 Jun 2026 NCT07300163
● Recruiting Phase III Oncology
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
What is being tested: Sacituzumab govitecan-hziyah (Sac-TMT), an antibody-drug conjugate targeting TROP-2, is being evaluated as a treatment option for advanced ovarian cancer patients…
22 Jun 2026 NCT07318558
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
New cancer drug inavolisib plus fulvestrant compared with alpelisib plus fulvestrant for advanced breast cancer resistant to previous treatments.
18 Jun 2026 NCT05646862
active not recruiting Diabetes / Metabolic
Effect of a Sugar Replacement on Blood Glucose Levels in Healthy Adults
A sugar replacement called Oligomate® lowered blood sugar spikes after drinking compared to glucose in healthy people.
18 Jun 2026 NCT06714552
active not recruiting Phase III Oncology
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Testing two immunotherapy combinations after chemotherapy and radiotherapy in advanced lung cancer patients.
18 Jun 2026 NCT05221840
● Recruiting Phase II Mental Health / Psychiatry
A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
Single dose of experimental drug SYT-510 tested against placebo in anxiety patients to assess safety, effectiveness and body response.
18 Jun 2026 NCT07478744
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Treatment being tested: KAI-9531, a novel subcutaneous injection administered weekly, is being evaluated for its efficacy in reducing body weight compared to placebo in…
18 Jun 2026 NCT07284875
● Recruiting Cardiology / Cardiovascular
Pancreas Lipotoxicity in T2D: Edinburgh Diabetes Remission Study (EDRS)
What is being tested: The study investigates pancreatic fat accumulation (lipotoxicity) as a mechanism in type 2 diabetes development and whether weight loss interventions…
18 Jun 2026 NCT07364045
● Recruiting Phase III Cardiology / Cardiovascular
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
What is being tested: Lepodisiran, an investigational therapy designed to reduce lipoprotein(a) [Lp(a)] levels, is being evaluated for its ability to reduce coronary artery…
18 Jun 2026 NCT07613294
● Recruiting Phase III Cardiology / Cardiovascular
Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage
What is being tested: The optimal timing for restarting direct oral anticoagulants (DOACs) in older patients after traumatic intracranial haemorrhage, comparing early versus delayed…
18 Jun 2026 NCT06322953
● Recruiting Phase III Oncology
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Treatment being tested: Two immunotherapy-based regimens for advanced biliary tract cancer (BTC)—rilvegostomig combined with gemcitabine/cisplatin versus durvalumab combined with gemcitabine/cisplatin—compared as first-line therapy in…
18 Jun 2026 NCT07221253
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician’s Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Giredestrant versus standard hormone therapy for early breast cancer: a Phase III trial testing a new treatment option.
18 Jun 2026 NCT04961996
active not recruiting Phase III
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren’s Syndrome
Trial testing whether ianalumab improves symptoms and safety in people with active Sjögren's syndrome compared to placebo.
18 Jun 2026 NCT05349214
active not recruiting Phase III Infectious Disease
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients
A new HIV drug (BMS-663068) tested in patients with resistant virus who have failed multiple previous treatments.
18 Jun 2026 NCT02362503
active not recruiting Phase III Diabetes / Metabolic
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
Retatrutide weekly injection tested to reduce heart attacks, strokes, and kidney damage in obese adults over five years.
18 Jun 2026 NCT06383390
active not recruiting Rheumatology
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Trial comparing patellar versus quadriceps tendon grafts for ACL reconstruction, with or without additional lateral stabilisation surgery.
18 Jun 2026 NCT03935750
active not recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
CAEL-101 antibody tested to remove amyloid deposits, improve survival and reduce heart hospitalisations in advanced light chain amyloidosis patients.
18 Jun 2026 NCT04512235
active not recruiting Phase III
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Imetelstat improves survival compared to standard treatment in patients with advanced myelofibrosis who haven't responded to JAK inhibitors.
18 Jun 2026 NCT04576156
● Recruiting Respiratory / COPD / Asthma
Serological and PCR Testing for COVID-19
What is being tested: The trial evaluates existing and newly developed COVID-19 PCR and antibody (serological) tests to establish methodologies that deliver rapid and…
18 Jun 2026 NCT04404062
● Recruiting Phase I Oncology
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
What is being tested: An umbrella trial evaluating multiple treatment combination regimens across seven cohorts in patients with metastatic or inoperable locally advanced breast…
18 Jun 2026 NCT03424005
● Recruiting Phase I Oncology
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
What is being tested: AZD4956, a novel investigational agent, is being evaluated as both a monotherapy and in combination with established anti-cancer treatments in…
18 Jun 2026 NCT07446855
● Recruiting Phase I Oncology
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
What is being tested: S241656 is a novel investigational agent being evaluated in a first-in-human trial as monotherapy and in combination with established anti-cancer…
18 Jun 2026 NCT05786924
● Recruiting Phase I
Phase 1 Study of ADX-626 in Healthy Participants
Early safety testing of new drug ADX-626 in healthy volunteers to check it's tolerable and how the body processes it.
17 Jun 2026 NCT07081503
active not recruiting Phase II Rheumatology
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
Trial testing IMVT-1402 injection versus placebo for skin lupus, measuring safety and effectiveness over 52 weeks.
17 Jun 2026 NCT06980805
active not recruiting Phase III Dermatology
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Ruxolitinib cream safely and effectively reduced moderate eczema in children and teenagers aged 6-17 years.
17 Jun 2026 NCT06832618
● Recruiting Cardiology / Cardiovascular
PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY
Remote weight monitoring with telephone doctor support reduces hospital admissions in patients with heart amyloidosis.
17 Jun 2026 NCT05098665
active not recruiting
Registry for Patients Undergoing Penile Prosthesis Implantation for Male Erectile Dysfunction
Registry tracking outcomes in men receiving surgical penile implants for erectile dysfunction.
17 Jun 2026 NCT03849586
active not recruiting Phase III Gastroenterology
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
Tofacitinib tablet oral treatment for children aged 2-17 with moderate-severe ulcerative colitis, measuring remission rates after 44 weeks.
17 Jun 2026 NCT04624230
● Recruiting Respiratory / COPD / Asthma
Breathlessness Perceptions Within Respiratory Diseases
What is being tested: This trial investigates how physiological, psychological, and functional factors—including breathing patterns—influence breathlessness perception in respiratory disease patients, moving beyond traditional…
17 Jun 2026 NCT07648082
● Recruiting Respiratory / COPD / Asthma
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
What is being tested: A randomized controlled trial evaluating whether patients with COPD and chronic bronchitis who switch from cigarette smoking to tobacco heating…
17 Jun 2026 NCT07108166
● Recruiting Cardiology / Cardiovascular
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
What is being tested: The study investigates the mechanisms of myocardial injury in rapid atrial fibrillation patients by measuring troponin levels (cardiac biomarker) and…
17 Jun 2026 NCT06951100
● Recruiting Oncology
Postoperative Electrical Muscle Stimulation Two
What is being tested: Electrical muscle stimulation (EMS) applied postoperatively to prevent or reduce skeletal muscle atrophy in patients experiencing immobility or inactivity following…
17 Jun 2026 NCT06964438
● Recruiting Phase II Neurology
A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson’s Disease
What is being tested: Dapansutrile, an anti-inflammatory medication that inhibits the NLRP3 inflammasome pathway, is being evaluated to determine whether reducing neuroinflammation can slow…
17 Jun 2026 NCT07157735
● Recruiting Phase II Neurology
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Treatment being tested: mRNA-1195, a novel mRNA-based therapeutic, is being investigated for its safety profile and tolerability in multiple sclerosis patients, with evaluation of…
17 Jun 2026 NCT06735248
● Recruiting Infectious Disease
Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients
What is being tested: Risk factors and clinical characteristics associated with ganciclovir-resistant or refractory cytomegalovirus (CMV) infection in immunocompromised patients following solid organ transplant…
17 Jun 2026 NCT05234723
● Recruiting Phase I Gastroenterology
A Phase 1/2, Open-Label, Single and Multiple Ascending Dose Study of CRMA-1001 in Adults With Chronic Hepatitis B
Drug being tested: CRMA-1001, a novel therapeutic agent undergoing Phase 1/2 evaluation for safety, tolerability, and efficacy in adults with chronic hepatitis B using…
17 Jun 2026 NCT07200193
● Recruiting Respiratory / COPD / Asthma
Innate Immunity in COPD
What is being tested: This trial investigates innate immune mechanisms in COPD to understand why some smokers develop the disease while others do not,…
17 Jun 2026 NCT05743582
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)
Treatment being tested: Axatilimab at three different dose levels in patients with recurrent or refractory active chronic graft versus host disease (cGVHD) who have…
17 Jun 2026 NCT04710576
● Recruiting Cardiology / Cardiovascular
RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure
What is being tested: BRITISH is evaluating whether implantable cardioverter-defibrillators (ICDs) improve outcomes in non-ischaemic cardiomyopathy patients with myocardial scar and severe systolic heart…
17 Jun 2026 NCT05568069
● Recruiting Cardiology / Cardiovascular
Thrombectomy in PE
What is being tested: Catheter-based thrombectomy (mechanical removal of blood clots using a special tube) as a treatment for pulmonary embolism, a potentially life-threatening…
17 Jun 2026 NCT07650435
● Recruiting Phase III Oncology
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Treatment being tested: Dato-DXd (a HER2-directed antibody-drug conjugate) combined with rilvegostomig (an immunostimulatory agent), versus rilvegostomig alone or pembrolizumab monotherapy, as first-line therapy for…
17 Jun 2026 NCT06357533
● Recruiting Phase I Oncology
A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas
Drug and Mechanism: STP938 (Dencatistat) is being tested as a monotherapy agent in a dose-escalation Phase 1 study followed by Phase 2 cohort expansion…
17 Jun 2026 NCT05463263
active not recruiting Phase I Oncology
A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
First-in-human trial testing safety, tolerability, and cancer-fighting activity of a new radioactive targeted treatment for advanced prostate cancer.
15 Jun 2026 NCT06052306
active not recruiting Phase III Infectious Disease
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy
Trial comparing a new two-drug HIV combination against standard three-drug treatment in people with well-controlled infection.
15 Jun 2026 NCT06333808
active not recruiting
Deuterium Labelled Carbohydrate Oxidation During High Intensity Exercise
Study using labelled glucose to measure how much glucose the body burns during moderate and high-intensity exercise.
15 Jun 2026 NCT07646665
active not recruiting Respiratory / COPD / Asthma
Experiences of Managing Sleep Disordered Breathing in Children With Cerebral Palsy.
Sleep breathing problems are common in children with cerebral palsy but often missed; this study explores patient and family experiences of treatment.
15 Jun 2026 NCT06753370
active not recruiting Phase I / Phase II Gastroenterology
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a “Shuttle”
Gene therapy trial testing safety and effectiveness of BAY 2599023 for severe hemophilia A treatment.
15 Jun 2026 NCT03588299