ClinicaliQ Trial Snapshot
- Innate Immunity in COPD — Recruiting • Respiratory / COPD / Asthma • NCT05743582.
- What is being tested: This trial investigates innate immune mechanisms in COPD to understand why some smokers develop the disease while others do not, potentially identifying biological markers and therapeutic targets.
- Patient eligibility overview: The study includes smokers with and without COPD, allowing comparison of immune responses between those who have developed airflow obstruction and those who remain unaffected despite smoking exposure.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Chronic Obstructive Pulmonary Disease (COPD) causes obstruction to airflow when breathing out. It is a leading cause of chronic lung disease, hospitalization and death. Smoking is the major cause of COPD but why some smokers develop COPD while others do not is poorly understood. A central feature of COPD is accumulation of inflammatory blood cells, macrophages and neutrophils, in the airway, leading to lung injury and airway damage. The small airways of many patients with COPD contain bacteria, which are absent in healthy smokers or non-smokers. These bacteria stimulate recruitment…
Eligibility Snapshot
- : COPD patients: * COPD patients aged 18-77 years who are GOLD Stage 1 or 2 or 3; for patients undergoing bronchoscopy already for a clinical reason. * COPD patients aged 18-77 years old who are GOLD Stage 1,2 or 3 for patients who are donating blood only. * COPD patients aged 18-69 years who are GOLD Stage 1 or 2 for patients undergoing bronchoscopy for research purposes. * COPD- Defined by radiological investigation of chest either chest X-ray or High-resolution CT scan in previous 12 months * Ability to provide informed consent Healthy volunteers: * Any healthy volunteer aged 18-77 years * Ability to provide informed consent
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.