Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Infectious Disease
Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients
Study examined risk factors for ganciclovir-resistant CMV infection in organ and stem cell transplant patients to improve future prevention and treatment.
15 Jun 2026 NCT05234723
active not recruiting Phase II / Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Adding inavolisib to standard breast cancer treatment improves outcomes in patients with specific genetic mutations and advanced hormone-receptor-positive disease.
15 Jun 2026 NCT04191499
active not recruiting Phase II
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Naxitamab (anti-GD2 antibody) plus GM-CSF treats high-risk neuroblastoma resistant to initial or salvage chemotherapy, with five-year follow-up.
15 Jun 2026 NCT03363373
● Recruiting
The UK 22 Week Study
Study observing outcomes in 22-week babies receiving active care across UK hospitals to identify common patterns and improve future treatment.
15 Jun 2026 NCT07616778
● Recruiting
Radiation Free Study
LumiGuide imaging reduces fluoroscopy time during complex aortic repair procedures compared to standard X-ray guidance.
15 Jun 2026 NCT06549348
● Recruiting
International CRDS Registry
A new registry tracks a rare genetic heart rhythm condition caused by RYR2 gene faults to understand its features and best treatments.
15 Jun 2026 NCT06508164
● Recruiting
PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB
A long-term safety and effectiveness study of the Axonics sacral nerve stimulation device for overactive bladder.
15 Jun 2026 NCT06789406
● Recruiting Cardiology / Cardiovascular
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
Study investigates whether heart damage markers in rapid atrial fibrillation patients indicate blocked arteries or heart attack.
15 Jun 2026 NCT06951100
● Recruiting Respiratory / COPD / Asthma
Breathlessness Perceptions Within Respiratory Diseases
What is being tested: This cross-sectional study investigates how physiological, psychological, functional, and breathing pattern factors influence breathlessness perception and health-related quality of life…
15 Jun 2026 NCT07648082
● Recruiting Phase I
Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants
Testing two new long-acting injectable medicines alone and combined for safety, tolerability and how the body processes them in healthy volunteers.
15 Jun 2026 NCT07011511
active not recruiting Phase I / Phase II Oncology
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
Trial testing a new breast cancer drug (elacestrant) combined with five existing treatments to find safe doses and effectiveness.
12 Jun 2026 NCT05563220
● Recruiting Phase III Neurology
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
Radiprodil versus placebo for rare genetic brain disorder causing seizures and developmental problems, with open-label extension.
12 Jun 2026 NCT07224581
● Recruiting Phase III Dermatology
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Trial testing whether subcutaneous mezagitamab maintains stable platelet counts in adults with immune thrombocytopenia compared to placebo.
12 Jun 2026 NCT06722235
● Recruiting Phase III Respiratory / COPD / Asthma
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Intervention being tested: Filgotinib, a JAK1-selective inhibitor, is being evaluated for efficacy, safety, tolerability, and pharmacokinetics in paediatric and adolescent patients with ulcerative colitis…
12 Jun 2026 NCT06865417
● Recruiting Phase I Oncology
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
What is being tested: AMG 410, a novel KRAS-targeted agent, is being evaluated as monotherapy and in combination regimens for safety, tolerability, pharmacokinetics, and…
12 Jun 2026 NCT07094113
● Recruiting Phase III Oncology
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
What is being tested: Belzutifan (MK-6482), a hypoxia-inducible factor (HIF-2α) inhibitor, is being evaluated in an extension study for patients with advanced solid tumors…
12 Jun 2026 NCT07405164
● Recruiting Phase III Cardiology / Cardiovascular
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
What is being tested: Sovateltide, a neuroprotective agent designed to protect brain tissue during acute ischaemic stroke and potentially promote neural repair in the…
12 Jun 2026 NCT05691244
● Recruiting Cardiology / Cardiovascular
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
What is being tested: Real-world effectiveness, safety, and treatment patterns of mavacamten (a novel cardiac myosin inhibitor) compared with standard therapies in symptomatic obstructive…
12 Jun 2026 NCT05489705
● Recruiting Phase III Oncology
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
What is being tested: IDRX-42 (GSK6042981), a novel investigational drug, is being evaluated against sunitinib (standard comparator) in adults with gastrointestinal stromal tumors (GIST)…
12 Jun 2026 NCT07218926
● Recruiting Phase III Oncology
A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study
What is being tested: Continued treatment with Roche investigational medicinal products (IMPs), either as monotherapy or in combination with other agents or comparators, in…
12 Jun 2026 NCT05862285
● Recruiting Phase II Oncology
Study of Olutasidenib and Temozolomide in HGG
What is being tested: Olutasidenib combined with temozolomide in newly diagnosed pediatric and young adult patients with IDH1-mutant high-grade gliomas (HGG), evaluating whether this…
12 Jun 2026 NCT06161974
active not recruiting Phase III Cardiology / Cardiovascular
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
Inclisiran injection reduces heart attacks, strokes, and cardiovascular deaths in high-risk patients without prior heart disease, compared to placebo.
12 Jun 2026 NCT05739383
● Recruiting
Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)
Observational study establishing a real-world comparison group of PSC patients to help design and evaluate future PSC treatment trials.
12 Jun 2026 NCT06297993
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
MET097 injected once weekly helped adults with obesity or overweight lose weight over 64 weeks of treatment.
12 Jun 2026 NCT07311850
active not recruiting Phase II
Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough
New inhaled powder drug tested against placebo for treating persistent cough that hasn't responded to standard treatments.
12 Jun 2026 NCT06504446
active not recruiting Phase II Neurology
Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension
Study tests whether adding venglustat to standard Gaucher disease treatment improves brain-related symptoms and safety in adults.
12 Jun 2026 NCT02843035
active not recruiting Phase II Respiratory / COPD / Asthma
Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
Long-term safety and effectiveness study of BI 1291583 tablet in adults with bronchiectasis who completed previous trials.
12 Jun 2026 NCT05846230
● Recruiting Phase II Oncology
RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive
Treatment being tested: RO7771950 (a novel HER2-directed tyrosine kinase inhibitor) combined with trastuzumab and capecitabine, compared against the established standard tucatinib-based regimen in HER2-positive…
12 Jun 2026 NCT07413939
● Recruiting Phase II Respiratory / COPD / Asthma
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
What is being tested: OHB-607, an investigational drug designed to prevent Bronchopulmonary Dysplasia (BPD) in extremely premature infants, evaluated against standard neonatal care alone…
12 Jun 2026 NCT03253263
● Recruiting Respiratory / COPD / Asthma
Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections
What is being tested: Photodynamic therapy (PDT) using the Steriwave™ ND System to prevent surgical site infections in patients undergoing nasal surgery, compared with…
12 Jun 2026 NCT06731881
● Recruiting Cardiology / Cardiovascular
Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)
What is being tested: The BRICCS Study examines diagnostic and prognostic factors in patients with established cardiovascular disease (coronary artery disease, heart failure, myocardial…
12 Jun 2026 NCT04388943
● Recruiting Phase I Oncology
Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
Therapeutic Target: XmAb®819 is being tested as a potential treatment for advanced clear cell renal cell carcinoma (ccRCC), specifically in patients with relapsed or…
12 Jun 2026 NCT05433142
● Recruiting Phase I Oncology
Dose Determining Study of EXS73565 in Participants With Relapsed or Refractory B-Cell Malignancies
What is being tested: EXS73565 is an oral investigational agent being evaluated for safety, tolerability, pharmacokinetics, and antitumor activity in a dose-determining study in…
12 Jun 2026 NCT06980116
● Recruiting Phase III Oncology
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
What is being tested: Long-term safety and clinical benefit of pelabresib (a BET inhibitor) in patients with hematological and/or solid tumors, including evaluation of…
12 Jun 2026 NCT06401356
active not recruiting Oncology
Granulocyte Transfusions After Umbilical Cord Blood Transplant
Study testing whether white blood cell transfusions improve immune recovery and outcomes after cord blood stem cell transplant in children with leukaemia.
09 Jun 2026 NCT05425043
active not recruiting Phase I Oncology
Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies
Trial testing safety and effectiveness of oral ABBV-101 alone or combined with venetoclax in adults with relapsed/refractory non-Hodgkin's lymphoma.
09 Jun 2026 NCT05753501
● Recruiting Phase I Oncology
A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)
Trial testing loncastuximab tesirine combined with three other drugs in patients with hard-to-treat B-cell lymphoma to find safe, effective doses.
09 Jun 2026 NCT04970901
● Recruiting Phase III Rheumatology
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
Trial testing deucravacitinib dosing, effectiveness and safety in children aged 4-17 with moderate-to-severe psoriasis over five years.
09 Jun 2026 NCT04772079
active not recruiting
Portico Next Generation Approval Study
Portico Next Generation Approval Study Study testing a new heart valve for high-risk patients, measuring safety at 30 days and leakage around the valve.
09 Jun 2026 NCT04011722
active not recruiting Oncology
Comprehensive Segmental Revision System
A study evaluating how well the Comprehensive Segmental Revision System works for complex spinal reconstruction surgery.
09 Jun 2026 NCT03270982
● Recruiting
An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment
Study tracking how routine preventative treatment works and affects quality of life in patients with Type 3 von Willebrand disease over 24 weeks.
09 Jun 2026 NCT06883240
● Recruiting Phase III Oncology
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Treatment being tested: Pirtobrutinib (LOXO-305), a novel BTK inhibitor, is being compared against ibrutinib (standard BTK inhibitor) in patients with chronic lymphocytic leukaemia/small lymphocytic…
09 Jun 2026 NCT05254743
● Recruiting Phase II Oncology
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
What is being tested: Adjuvant autogene cevumeran (personalised neoantigen vaccine) combined with atezolizumab (PD-L1 inhibitor) plus mFOLFIRINOX chemotherapy versus mFOLFIRINOX chemotherapy alone in patients…
09 Jun 2026 NCT05968326
● Recruiting Phase I Oncology
A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
What is being tested: AZD6621, an experimental therapeutic agent, is undergoing evaluation for safety, tolerability, pharmacokinetics, and efficacy in adult male patients with metastatic…
09 Jun 2026 NCT07192614
active not recruiting Phase II Oncology
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
Trial testing targeted cancer drugs based on tumour genetic markers in women with rare, recurrent ovarian cancer.
08 Jun 2026 NCT04931342
active not recruiting Phase III Neurology
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
Fingolimod was safer and more effective than interferon beta-1a for reducing MS relapses in children.
08 Jun 2026 NCT01892722
active not recruiting Phase I
Study of E7386 in Participants With Selected Advanced Neoplasms
A study testing an oral cancer drug (E7386) to find safe doses and assess side effects in patients with advanced cancers.
08 Jun 2026 NCT03264664
active not recruiting Phase III Oncology
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Two drug combination therapy compared with single drug treatment for advanced lung cancer with specific genetic mutations.
08 Jun 2026 NCT04487080
● Recruiting Phase II
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves’ Disease
New drug IMVT-1402 tested against placebo in patients with Graves' disease uncontrolled by standard thyroid medications.
08 Jun 2026 NCT07018323
active not recruiting Phase III
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients
Crizanlizumab at two different doses tested against placebo to reduce pain crises in adolescents and adults with sickle cell disease.
08 Jun 2026 NCT03814746