ClinicaliQ Trial Snapshot
- Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage — Recruiting • Phase III • Cardiology / Cardiovascular • NCT06322953.
- What is being tested: The optimal timing for restarting direct oral anticoagulants (DOACs) in older patients after traumatic intracranial haemorrhage, comparing early versus delayed reinitiation strategies to balance stroke prevention against rebleeding risk.
- Patient eligibility overview: Older adults admitted with traumatic intracranial haemorrhage who were taking oral anticoagulants prior to injury, representing a common clinical scenario affecting approximately 1 in 3 head injury admissions in this population.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Older people falling from a standing height is the most common cause of hospital admission for head injury. Up to 1 in 3 patients admitted are taking a tablet medication which thins the blood, known as an oral anticoagulant. This type of medication can increase the likelihood of bleeding in the brain. Many patients are taking oral anticoagulation due to having an irregular heartbeat (called atrial fibrillation) or because of having a previous stroke or blood clots. When a scan shows blood in the brain, oral anticoagulation is nearly always…
Eligibility Snapshot
- : 1. Informed consent obtained from participant / participants' legal representative and ability to comply with the requirements of the trial
- Adult ≥18 years with traumatic intracranial haemorrhage (tICrH) in the past 1 week who were taking oral anticoagulants (OAC) prior to admission (Oral anticoagulants include any DOAC or Vitamin K antagonist (e.g. Warfarin), prescribed for atrial fibrillation (AF)/ atrial flutter, or venous thromboembolism (VTE) prior to admission for tICrH)
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.