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Clinical Trial ● Currently Recruiting Phase II NCT07033494

A Clinical Study of MK-2214 in People With Early Alzheimer’s Disease (MK-2214-004)

A Clinical Study of MK-2214 in People With Early Alzheimer’s Disease (MK-2214-004) — Recruiting • Phase II • Cardiology / Cardiovascular • NCT07033494.

📅 25 Mar 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II
NCT ID
NCT07033494
Sponsor
Merck Sharp & Dohme LLC
Start
2025-07-16
ClinicaliQ Trial Snapshot
  • A Clinical Study of MK-2214 in People With Early Alzheimer’s Disease (MK-2214-004) — Recruiting • Phase II • Cardiology / Cardiovascular • NCT07033494.
  • Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). AD is a type of dementia that can cause loss of memory, communication (such as speech), and decision-making….
  • Sponsor: Merck Sharp & Dohme LLC.

Verify eligibility, endpoints and current status on the original source registry before acting on this summary.

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What This Trial Is Studying

Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). AD is a type of dementia that can cause loss of memory, communication (such as speech), and decision-making skills. It can limit a person's ability to do daily tasks. MK-2214 is a study treatment designed to slow down AD. The goals of the study are to learn: * If MK-2214 slows the spread of tau in the brain compared to placebo. Tau is a protein that…

Eligibility Snapshot
  • : The main inclusion criteria include but are not limited to the following: * Has mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD) * Has a designated study partner who can fulfill the requirements of this study * If on an approved AD therapy for symptomatic AD, the dosing regimen must have been stable for 3 months prior to screening

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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