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Clinical Trial ● Currently Recruiting Non-phase study NCT06488638

Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF) — Recruiting • Non-phase study • Respiratory / COPD / Asthma • NCT06488638.

📅 30 Jun 2026 ⏱ 3 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Non-phase study
NCT ID
NCT06488638
Sponsor
University Hospital Southampton NHS Foundation Trust
Start
2026-02-13
ClinicaliQ Trial Snapshot
  • Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF) — Recruiting • Non-phase study • Respiratory / COPD / Asthma • NCT06488638.
  • What is being tested: Nitrate-rich beetroot juice supplementation as a potential intervention to improve exercise capacity in IPF patients, building on evidence that interval-based exercise programmes enhance functional outcomes in this population.
  • Patient eligibility overview: Adults with confirmed idiopathic pulmonary fibrosis diagnosis; specific age, disease severity, and functional status criteria would typically apply, though full eligibility details require the complete protocol.
Use This Page For
  • Quick orientation before opening the registry record.
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  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Idiopathic pulmonary fibrosis (IPF) is a type of scarring (fibrotic) lung disease. Reduced exercise capacity is a key symptom experienced by patients. In previous research the investigators identified that an interval-based exercise programme led to significant improvements in exercise capacity (Wallis et al Antioxidants. 2023). An unexpected finding was that in patients with IPF, exercise led to a reduction in blood nitrite concentrations an observation the investigators did not see in non-affected individuals. Research has identified that nitrite concentrations are expected to increase after exercise and the size of this…

Eligibility Snapshot
  • IPF Patients: Inclusion Criteria 1. Patients aged 18-85 years with a prior specialist multidisciplinary team diagnosis of idiopathic pulmonary fibrosis (IPF) based on current established consensus guidelines. 2. Medical Research Council (MRC) breathlessness grade 1-3 3. Judged clinically stable for 3 months prior to recruitment by the investigator. IPF Patients:

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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