- Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF) — Recruiting • Non-phase study • Respiratory / COPD / Asthma • NCT06488638.
- What is being tested: Nitrate-rich beetroot juice supplementation as a potential intervention to improve exercise capacity in IPF patients, building on evidence that interval-based exercise programmes enhance functional outcomes in this population.
- Patient eligibility overview: Adults with confirmed idiopathic pulmonary fibrosis diagnosis; specific age, disease severity, and functional status criteria would typically apply, though full eligibility details require the complete protocol.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
Idiopathic pulmonary fibrosis (IPF) is a type of scarring (fibrotic) lung disease. Reduced exercise capacity is a key symptom experienced by patients. In previous research the investigators identified that an interval-based exercise programme led to significant improvements in exercise capacity (Wallis et al Antioxidants. 2023). An unexpected finding was that in patients with IPF, exercise led to a reduction in blood nitrite concentrations an observation the investigators did not see in non-affected individuals. Research has identified that nitrite concentrations are expected to increase after exercise and the size of this…
- IPF Patients: Inclusion Criteria 1. Patients aged 18-85 years with a prior specialist multidisciplinary team diagnosis of idiopathic pulmonary fibrosis (IPF) based on current established consensus guidelines. 2. Medical Research Council (MRC) breathlessness grade 1-3 3. Judged clinically stable for 3 months prior to recruitment by the investigator. IPF Patients:
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.