ClinicaliQ Trial Snapshot
- Study of CryptiVax-1001 in Maintenance Setting for Advanced Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer — Recruiting • Phase I • Oncology • NCT07665515.
- What is being tested: CryptiVax-1001, an immunotherapeutic vaccine, is being evaluated as a maintenance treatment in patients with advanced high-grade serous ovarian, fallopian tube, or primary peritoneal cancer who have responded to standard chemotherapy.
- Patient eligibility overview: The trial includes patients with advanced serous ovarian cancer (stages III-IV) who have achieved disease control following platinum-based chemotherapy and are eligible for maintenance therapy without evidence of active disease progression.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Ovarian, fallopian tube, or primary peritoneal cancer, collectively referred to as ovarian cancer, remains the deadliest type of gynaecological cancer. The most common and aggressive form is called high-grade serous ovarian cancer. The main purpose of this study is to understand whether an experimental study vaccine, CryptiVax-1001, is safe when administered to patients with high-grade serous ovarian cancer (HGSOC). The study vaccine is a cancer vaccine, which aims to delay or possibly prevent the cancer from coming back. However, as this is the first study of the vaccine in patients,…
Eligibility Snapshot
- : * Able to comprehend and are willing to sign the ICF and willing to follow the study procedures * Female, aged 18 years of age or older at the time of informed consent. * Histologically confirmed diagnosis of epithelial ovarian, fallopian tube, or primary peritoneal carcinoma of high-grade serous histology or other high-grade predominantly serous subtypes * The FIGO 2014 stage III or IV disease at initial diagnosis. * Underwent optimal PDS or IDS with residual disease ≤1 cm (R0 or R1 resection) * Completed first-line platinum-based chemotherapy (minimum 4 cycles of carboplatin and paclitaxel, or equivalent, received in either neoadjuvant or adjuvant, or both settings). * In the presence of measurable target lesion, achieved CR or PR per investigator assessment based on RECIST 1.1 after completion of chemotherapy. In the absence of measurable target lesion, no new lesion or overt progression per investigator assessment based on RECIST 1.1 after completion of chemotherapy. * A minimum of 4 weeks from screening since the last dose of first-line platinum-based chemotherapy but not more than 12 weeks from screening since the last dose of first-line platinum-based chemotherapy. * No evidence of radiologic or clinical progression between the end of chemotherapy…
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.