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Clinical Trial ● Currently Recruiting Phase III NCT06819891

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn’s Disease

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn’s Disease — Recruiting • Phase III…

📅 06 Jul 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT06819891
Start
2025-05-12
Completion
2028-12-31
ClinicaliQ Trial Snapshot
  • A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn’s Disease — Recruiting • Phase III • Gastroenterology • NCT06819891.
  • This trial tests a new drug called Afimkibart to treat moderate-to-severe Crohn's disease, comparing it against placebo.

Verify eligibility, endpoints and current status on the original ClinicalTrials.gov registry before acting on this summary.

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What This Trial Is Studying

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD). Conditions: Moderately to Severely Active Crohns Disease Interventions: Afimkibart, Placebo Lead Sponsor: Hoffmann-La Roche Planned Enrollment: 425 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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