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Clinical Trial ● Currently Recruiting Non-phase study NCT05633303

Personalised Ablation Strategies in AF

Personalised Ablation Strategies in AF — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT05633303.

📅 08 May 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Non-phase study
NCT ID
NCT05633303
Sponsor
Barts & The London NHS Trust
Start
2022-10-14
ClinicaliQ Trial Snapshot
  • Personalised Ablation Strategies in AF — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT05633303.
  • What is being tested: Personalised ablation strategies for atrial fibrillation that move beyond standard one-size-fits-all approaches to customise treatment based on individual patient characteristics and AF substrate.
  • Patient eligibility overview: Adults with atrial fibrillation suitable for catheter ablation, with the trial likely including both paroxysmal and persistent AF patients stratified by baseline clinical and anatomical features.
Use This Page For
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  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Atrial fibrillation (AF) is the most common arrhythmia with an expected rise in prevalence over the next decade. Catheter ablation is a safe treatment option in eliminating AF however, success rates still remains variable. Existing strategies do not take into account the differences in AF perpetuation mechanisms beyond the pulmonary veins (PVs) due to the underlying substrate. Here, I will investigate the differences in persistent AF mechanisms due to the underlying substrate and utilise these findings to generate AF mechanism specific ablation strategies. I have defined a new metric, rate-dependent…

Eligibility Snapshot
  • : * Patients undergoing catheter ablation for persistent AF (

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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