ClinicaliQ Trial Snapshot
- Placental Biology in Health and Disease — Recruiting • Cardiology / Cardiovascular • NCT07470320.
- What is being tested: This trial investigates placental biological mechanisms underlying pre-eclampsia (hypertension with organ damage) and gestational diabetes mellitus (abnormal glucose metabolism in pregnancy), both conditions associated with serious maternal and fetal complications including fetal growth restriction.
- Patient eligibility overview: The study enrolls pregnant women across the full spectrum of placental health—from those with normal pregnancies to those diagnosed with pre-eclampsia, gestational diabetes, fetal growth restriction, or combinations thereof—enabling direct comparison of placental function across disease states.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR). Gestational diabetes mellitus (GDM) involves abnormal blood sugar levels during pregnancy and can have both short and long-term impacts on the health of the mother and child. Both conditions are linked to placental dysfunction but the precise mechanisms behind these links remain unclear. A major focus of this study is on extracellular vesicles (EVs) which are tiny, bubble-like particles…
Eligibility Snapshot
- : * Female, aged 18 years or above * Willing and able to give informed consent for participation in the study * Able to read and understand written and spoken English to comprehend study materials and give informed consent * Non-pregnant women in good general health OR pregnant women who fall into one of the following: * Healthy pregnancy * Pre-eclampsia (PET) - defined by clinical diagnostic criteria, including hypertension and proteinuria * Gestational diabetes mellitus (GDM) - diagnosed by standard glucose tolerance tests during pregnancy * Fetal growth restriction (FGR) - diagnosed based on fetal weight or Doppler abnormalities * Predisposed to PET - high-risk factors for PET such as maternal type 1 or type 2 diabetes, autoimmune diseases or multiple pregnancies
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.