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Clinical Trial Active — Not Recruiting Phase III NCT05425940

Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer

Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer — Active Not Recruiting • Phase III • Oncology • NCT05425940.

📅 17 Jul 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05425940
Start
2022-09-07
Completion
2026-06-16
ClinicaliQ Trial Snapshot
  • Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer — Active Not Recruiting • Phase III • Oncology • NCT05425940.
  • New drug combination XL092 plus atezolizumab compared to regorafenib for advanced bowel cancer that hasn't responded to standard treatment.

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What This Trial Is Studying

The primary purpose of this study is to evaluate XL092 + atezolizumab versus regorafenib in participants with microsatellite stable/microsatellite instability low (MSS/MSI-low) metastatic colorectal cancer (mCRC) who have progressed during, after or are intolerant to standard-of-care (SOC) therapy. Conditions: Colorectal Cancer Interventions: XL092, Atezolizumab, Regorafenib Lead Sponsor: Exelixis Planned Enrollment: 901 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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