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Clinical Trial ● Currently Recruiting Phase I NCT04068597

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies — Recruiting • Phase I • Oncology • NCT04068597.

📅 24 Jun 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase I
NCT ID
NCT04068597
Sponsor
CellCentric Ltd.
Start
2019-08-09
ClinicaliQ Trial Snapshot
  • Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies — Recruiting • Phase I • Oncology • NCT04068597.
  • Drug being tested: CCS1477 (inobrodib), a novel therapeutic agent being evaluated for safety, tolerability, pharmacokinetics and biological activity in a Phase 1/2a trial across four haematological malignancies (Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukaemia, and High Risk Myelodysplastic Syndrome).
  • Patient eligibility: The study enrolls patients with confirmed diagnoses of Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukaemia, or High Risk Myelodysplastic Syndrome; specific eligibility criteria including disease status, prior treatment history and performance status would be detailed in the full protocol.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

A Phase 1/2a study to assess the safety, tolerability, PK and biological activity of CCS1477 (inobrodib) in patients with Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukaemia or High Risk Myelodysplastic syndrome.

Eligibility Snapshot
  • : * Provision of consent * ECOG performance status 0-2 * Patients with confirmed (per standard disease specific diagnostic criteria), relapsed or refractory haematological malignancies (NHL, MM and AML) * Must have previously received standard therapy * Adequate organ function

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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