- Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma — Active Not Recruiting • Phase II • Oncology • NCT06703346.
- Engineered T-cell therapy trial testing safety and effectiveness in advanced synovial sarcoma or liposarcoma patients.
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This trial will evaluate safety and efficacy of human engineered T-cell therapies, in participants with advanced tumors. This trial is a sub study of the Master study NCT03967223. Conditions: Neoplasms Interventions: Letetresgene autoleucel (Lete-Cel (GSK3377794)), Cyclophosphamide, Fludarabine Lead Sponsor: USWM CT, LLC Planned Enrollment: 87 participants