- Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma — Active Not Recruiting • Phase II • Oncology • NCT05993299.
- Gene-edited T-cell therapy trial testing safety and effectiveness in advanced synovial sarcoma and liposarcoma patients.
Verify eligibility, endpoints and current status on the original ClinicalTrials.gov registry before acting on this summary.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
This trial will evaluate safety and efficacy of human engineered T-cell therapies, in participants with advanced tumors. This trial is a sub study of the Master study NCT03967223. Conditions: Neoplasms Interventions: Letetresgene autoleucel, Cyclophosphamide, Fludarabine Lead Sponsor: USWM, LLC (dba US WorldMeds) Planned Enrollment: 7 participants